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KIF2B antibody (AA 1607-1731)

KIF2B Reactivity: Human ELISA, IHC, IF Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7157616
  • Target See all KIF2B Antibodies
    KIF2B (Kinesin Family Member 2B (KIF2B))
    Binding Specificity
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 1607-1731
    Reactivity
    • 19
    • 6
    • 5
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 19
    Rabbit
    Clonality
    • 19
    Polyclonal
    Conjugate
    • 10
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This KIF2B antibody is un-conjugated
    Application
    • 9
    • 6
    • 3
    • 2
    • 1
    • 1
    ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
    Cross-Reactivity
    Human
    Purification
    >95%, Protein G purified
    Immunogen
    Recombinant Human Kinesin-like protein KIF20B protein (1607-1731AA)
    Isotype
    IgG
  • Application Notes
    Recommended dilution: IHC:1:200-1:500, IF:1:50-1:200,
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C,-80 °C
    Storage Comment
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target
    KIF2B (Kinesin Family Member 2B (KIF2B))
    Alternative Name
    KIF2B (KIF2B Products)
    Synonyms
    1700063D03Rik antibody, QtsA-13688 antibody, QtsA-18420 antibody, kinensin antibody, kinesin family member 2B antibody, Kif2b antibody, KIF2B antibody
    Background

    Background: Plus-end-directed motor enzyme that is required for completion of cytokinesis (PubMed:11470801, PubMed:12740395). Required for proper midbody organization and abscission in polarized cortical stem cells. Plays a role in the regulation of neuronal polarization by mediating the transport of specific cargos. Participates in the mobilization of SHTN1 and in the accumulation of PIP3 in the growth cone of primary hippocampal neurons in a tubulin and actin-dependent manner. In the developing telencephalon, cooperates with SHTN1 to promote both the transition from the multipolar to the bipolar stage and the radial migration of cortical neurons from the ventricular zone toward the superficial layer of the neocortex. Involved in cerebral cortex growth (By similarity). Acts as an oncogene for promoting bladder cancer cells proliferation, apoptosis inhibition and carcinogenic progression (PubMed:17409436).

    Aliases: Cancer/testis antigen 90 antibody, CT90 antibody, KI20B_HUMAN antibody, KIF20B antibody, Kinesin-like protein KIF20B antibody, Kinesin-related motor interacting with PIN1 antibody, KRMP1 antibody, M-phase phosphoprotein 1 antibody, MPHOSPH1 antibody, MPP 1 antibody, Mpp1 antibody

    UniProt
    Q96Q89
    Pathways
    Microtubule Dynamics
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