F11R antibody (AA 31-224)

Catalog No. ABIN7157166

Product Details anti-F11R Antibody

Target: F11R (F11 Receptor (F11R))

Binding Specificity: AA 31-224

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This F11R antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Junctional adhesion molecule A protein (31-224AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for F11R

Target: F11R (F11 Receptor (F11R))

Alternative Name: F11R (F11R Products)

Synonyms: CD321 antibody, JAM antibody, JAM1 antibody, JAMA antibody, JCAM antibody, KAT antibody, PAM-1 antibody, 9130004G24 antibody, AA638916 antibody, ESTM33 antibody, JAM-1 antibody, JAM-A antibody, Jcam antibody, Jcam1 antibody, Ly106 antibody, Jam1 antibody, F11 receptor antibody, F11R antibody, F11r antibody

Background:

Background: Seems to play a role in epithelial tight junction formation. Appears early in primordial forms of cell junctions and recruits PARD3 (PubMed:11489913). The association of the PARD6-PARD3 complex may prevent the interaction of PARD3 with JAM1, thereby preventing tight junction assembly (By similarity). Plays a role in regulating monocyte transmigration involved in integrity of epithelial barrier (By similarity). Ligand for integrin alpha-L/beta-2 involved in memory T-cell and neutrophil transmigration (PubMed:11812992). Involved in platelet activation (PubMed:10753840).

Aliases: CD 321 antibody, CD321 antibody, CD321 antigen antibody, ESTM33 antibody, F11 receptor antibody, F11R antibody, JAM 1 antibody, JAM A antibody, JAM antibody, JAM-1 antibody, JAM-A antibody, JAM1 antibody, JAM1_HUMAN antibody, JAMA antibody, JCAM antibody, Jcam1 antibody, Junction adhesion molecule 1 antibody, Junction adhesion molecule, mouse, homolog of antibody, Junctional adhesion molecule 1 antibody, Junctional adhesion molecule A antibody, KAT antibody, Ly106 antibody, PAM 1 antibody, PAM-1 antibody, PAM1 antibody, Platelet adhesion molecule 1 antibody, Platelet adhesion molecule antibody, Platelet F11 receptor antibody, PRO301 antibody, UNQ264 antibody

UniProt: Q9Y624

Pathways: Cell-Cell Junction Organization