JMJD5 antibody (AA 151-380) (Biotin)

Catalog No. ABIN7157151

Product Details anti-JMJD5 Antibody (Biotin)

Target: JMJD5 (Jumonji Domain Containing 5 (JMJD5))

Binding Specificity: AA 151-380

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This JMJD5 antibody is conjugated to Biotin

Application: ELISA

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human JmjC domain-containing protein 5 protein (151-380AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for JMJD5

Target: JMJD5 (Jumonji Domain Containing 5 (JMJD5))

Alternative Name: KDM8 (JMJD5 Products)

Synonyms: jmjd5 antibody, JMJD5 antibody, 3110005O21Rik antibody, Jmjd5 antibody, zgc:173863 antibody, zgc:91962 antibody, RGD1304823 antibody, lysine demethylase 8 antibody, jumonji domain containing 5 antibody, hypothetical protein antibody, lysine (K)-specific demethylase 8 antibody, KDM8 antibody, PTRG_02386 antibody, MCYG_00400 antibody, CC1G_13927 antibody, PGTG_16928 antibody, kdm8 antibody, Kdm8 antibody

Background:

Background: Histone demethylase required for G2/M phase cell cycle progression. Specifically demethylates dimethylated \\\'Lys-36\\\' (H3K36me2) of histone H3, an epigenetic repressive mark, thereby acting as a transcription activator. Regulates expression of CCNA1 (cyclin-A1), leading to regulate cancer cell proliferation.

Aliases: FLJ13798 antibody, JmjC domain-containing protein 5 antibody, JMJD5 antibody, JMJD5 protein antibody, jumonji domain containing 5 antibody, Jumonji domain-containing protein 5 antibody, KDM8_HUMAN antibody, Lysine (K) specific demethylase 8 antibody, Lysine-specific demethylase 8 antibody

UniProt: Q8N371

Pathways: Chromatin Binding