IZUMO1 antibody (AA 22-292)

Catalog No. ABIN7157142

Product Details anti-IZUMO1 Antibody

Target: IZUMO1 (Izumo Sperm-Egg Fusion 1 (IZUMO1))

Binding Specificity: AA 22-292

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IZUMO1 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Izumo sperm-egg fusion protein 1 protein (22-292AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for IZUMO1

Target: IZUMO1 (Izumo Sperm-Egg Fusion 1 (IZUMO1))

Alternative Name: IZUMO1 (IZUMO1 Products)

Synonyms: IZUMO antibody, 1700058F15Rik antibody, Izumo antibody, izumo sperm-egg fusion 1 antibody, Ras interacting protein 1 antibody, IZUMO1 antibody, RASIP1 antibody, Izumo1 antibody

Background:

Background: Essential sperm cell-surface protein required for fertilization by acting as a ligand for IZUMO1R/JUNO receptor on egg. The IZUMO1:IZUMO1R/JUNO interaction is a necessary adhesion event between sperm and egg that is required for fertilization but is not sufficient for cell fusion. The ligand-receptor interaction probably does not act as a membrane \'fusogen\'.

Aliases: FLJ61440 antibody, IZUM1_HUMAN antibody, IZUMO antibody, Izumo sperm egg fusion 1 antibody, Izumo sperm-egg fusion protein 1 antibody, Izumo1 antibody, MGC34799 antibody, OBF antibody, Oocyte binding/fusion factor antibody, Sperm specific protein izumo antibody, Sperm-specific protein izumo antibody

UniProt: Q8IYV9