IQCB1 antibody (AA 445-598)

Catalog No. ABIN7157026

Product Details anti-IQCB1 Antibody

Target: IQCB1 (IQ Motif Containing B1 (IQCB1))

Binding Specificity: AA 445-598

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IQCB1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Cross-Reactivity: Human, Mouse, Rat

Purification: >95%, Protein G purified

Immunogen: Recombinant Human IQ calmodulin-binding motif-containing protein 1 protein (445-598AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for IQCB1

Target: IQCB1 (IQ Motif Containing B1 (IQCB1))

Alternative Name: IQCB1 (IQCB1 Products)

Synonyms: piq antibody, nphp5 antibody, slsn5 antibody, MGC81507 antibody, IQCB1 antibody, zgc:101792 antibody, MGC146213 antibody, 6820449I09Rik antibody, AV128382 antibody, NPHP5 antibody, PIQ antibody, SLSN5 antibody, IQ motif containing B1 antibody, IQ motif containing B1 L homeolog antibody, IQ calmodulin-binding motif containing 1 antibody, Iqcb1 antibody, iqcb1.L antibody, IQCB1 antibody, iqcb1 antibody

Background:

Background: Involved in ciliogenesis. The function in an early step in cilia formation depends on its association with CEP290/NPHP6 (PubMed:21565611, PubMed:23446637). Involved in regulation of the BBSome complex integrity, specifically for presence of BBS2 and BBS5 in the complex, and in ciliary targeting of selected BBSome cargos. May play a role in controlling entry of the BBSome complex to cilia possibly implicating CEP290/NPHP6 (PubMed:25552655).

Aliases: IQ calmodulin-binding motif containing 1 antibody, IQ calmodulin-binding motif-containing protein 1 antibody, IQ motif containing B1 antibody, Iqcb1 antibody, IQCB1_HUMAN antibody, KIAA0036 antibody, Nephrocystin-5 antibody, NPHP5 antibody, p53 and DNA damage-regulated IQ motif protein antibody, SLSN5 antibody

UniProt: Q15051