IYD antibody (AA 24-147) (Biotin)

Catalog No. ABIN7157023

Product Details anti-IYD Antibody (Biotin)

Target: IYD (Iodotyrosine Deiodinase (IYD))

Binding Specificity: AA 24-147

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IYD antibody is conjugated to Biotin

Application: ELISA

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Iodotyrosine deiodinase 1 protein (24-147AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for IYD

Target: IYD (Iodotyrosine Deiodinase (IYD))

Alternative Name: IYD (IYD Products)

Synonyms: MGC85450 antibody, C6orf71 antibody, DEHAL1 antibody, TDH4 antibody, dJ422F24.1 antibody, 0610009A07Rik antibody, AI265638 antibody, Dehal1 antibody, RGD1309288 antibody, IYD-1 antibody, iodotyrosine deiodinase antibody, iodotyrosine deiodinase L homeolog antibody, IYD antibody, iyd.L antibody, iyd antibody, Iyd antibody

Background:

Background: Catalyzes the oxidative NADPH-dependent deiodination of monoiodotyrosine (L-MIT) or diiodotyrosine (L-DIT) (PubMed:15289438, PubMed:25395621, PubMed:18434651). Acts during the hydrolysis of thyroglobulin to liberate iodide, which can then reenter the hormone-producing pathways (PubMed:18434651). Acts more efficiently on monoiodotyrosine than on diiodotyrosine (PubMed:15289438).

Aliases: IYD antibody, C6orf71 antibody, DEHAL1 antibody, Iodotyrosine deiodinase 1 antibody, IYD-1 antibody, EC 1.21.1.1 antibody, Iodotyrosine dehalogenase 1 antibody

UniProt: Q6PHW0

Pathways: Thyroid Hormone Synthesis