IFT57 antibody (AA 170-429)
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- Target See all IFT57 Antibodies
- IFT57 (Intraflagellar Transport 57 Homolog (IFT57))
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Binding Specificity
- AA 170-429
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This IFT57 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (IHC), ELISA
- Cross-Reactivity
- Human, Mouse
- Purification
- Antigen Affinity Purified
- Immunogen
- Recombinant Human Intraflagellar transport protein 57 homolog protein (170-429AA)
- Isotype
- IgG
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- Application Notes
- Recommended dilution: WB:1:500-1:2000, IHC:1:20-1:200,
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Target
- IFT57 (Intraflagellar Transport 57 Homolog (IFT57))
- Alternative Name
- IFT57 (IFT57 Products)
- Synonyms
- Esrrbl1 antibody, 4833420A15Rik antibody, Hippi antibody, MHS4R2 antibody, ESRRBL1 antibody, HIPPI antibody, intraflagellar transport 57 antibody, intraflagellar transport 57 S homeolog antibody, Ift57 antibody, IFT57 antibody, ift57.S antibody
- Background
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Background: Required for the formation of cilia. Plays an indirect role in sonic hedgehog signaling, cilia being required for all activity of the hedgehog pathway (By similarity). Has pro-apoptotic function via its interaction with HIP1, leading to recruit caspase-8 (CASP8) and trigger apoptosis. Has the ability to bind DNA sequence motif 5\\\'-AAAGACATG-3\\\' present in the promoter of caspase genes such as CASP1, CASP8 and CASP10, suggesting that it may act as a transcription regulator, however the relevance of such function remains unclear.
Aliases: CDNA FLJ10147 fis clone HEMBA1003369 antibody, Dermal papilla derived protein 8 antibody, Dermal papilla-derived protein 8 antibody, DERP 8 antibody, DERP8 antibody, Esrrbl 1 antibody, Esrrbl1 antibody, ESRRBL1 protein antibody, Estrogen related receptor beta like 1 antibody, Estrogen related receptor beta like protein 1 antibody, Estrogen-related receptor beta-like protein 1 antibody, FLJ10147 antibody, Hip1 Interacting protein antibody, HIP1 interacting protein HIPPI antibody, Hip1 protein interactor antibody, HIP1-interacting protein antibody, HIPPI antibody, Huntingtin interacting protein 1 interacting protein antibody, Huntingtin interacting protein 1 protein interactor antibody, IFT 57 antibody, ift57 antibody, IFT57_HUMAN antibody, Intraflagellar transport 57 homolog (Chlamydomonas) antibody, Intraflagellar transport 57 homolog antibody, Intraflagellar transport protein 57 homolog antibody, MHS4R2 antibody, Vestrogen related receptor beta like 1 antibody
- UniProt
- Q9NWB7
- Pathways
- Hedgehog Signaling, Positive Regulation of Endopeptidase Activity
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