FIL1d antibody (AA 1-155)

Catalog No. ABIN7156908

Product Details anti-FIL1d Antibody

Target: FIL1d (Interleukin 1 delta (FIL1d))

Binding Specificity: AA 1-155

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FIL1d antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Cross-Reactivity: Human

Purification: Antigen Affinity Purified

Immunogen: Recombinant Human Interleukin-36 receptor antagonist protein (1-155AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: IHC:1:20-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for FIL1d

Target: FIL1d (Interleukin 1 delta (FIL1d))

Alternative Name: IL36RN (FIL1d Products)

Synonyms: AI413231 antibody, Fil1delta antibody, IL36RN antibody, Il-1h3 antibody, Il1hy1 antibody, FIL1 antibody, FIL1(DELTA) antibody, FIL1D antibody, IL1F5 antibody, IL1HY1 antibody, IL1L1 antibody, IL1RP3 antibody, IL36RA antibody, PSORP antibody, Il1f5 antibody, interleukin 1 family, member 5 (delta) antibody, interleukin 36 receptor antagonist antibody, Il1f5 antibody, IL36RN antibody, Il36rn antibody

Background:

Background: Inhibits the activity of interleukin-36 (IL36A,IL36B and IL36G) by binding to receptor IL1RL2 and preventing its association with the coreceptor IL1RAP for signaling. Part of the IL-36 signaling system that is thought to be present in epithelial barriers and to take part in local inflammatory response, similar to the IL-1 system with which it shares the coreceptor. Proposed to play a role in skin inflammation. May be involved in the innate immune response to fungal pathogens, such as Aspergillus fumigatus. May activate an anti-inflammatory signaling pathway by recruiting SIGIRR.

Aliases: AI413231 antibody, Family of interleukin 1 delta antibody, FIL1 antibody, FIL1 delta antibody, FIL1(DELTA) antibody, FIL1D antibody, Fil1delta antibody, I36RA_HUMAN antibody, IL 1 delta antibody, IL 1 related protein 3 antibody, IL 1F5 (IL 1HY1, FIL1 delta, IL 1RP3, IL 1L1, IL 1 delta) antibody, Il 1h3 antibody, IL 1HY1 antibody, IL 1L1 antibody, IL 1ra homolog antibody, IL 1ra homolog, IL1F5 (Canonical product IL 1F5a) antibody, IL 1RP3 antibody, IL-1 delta antibody, IL-1-related protein 3 antibody, IL-1F5 antibody, IL-1HY1 antibody, IL-1L1 antibody, IL-1ra homolog 1 antibody, IL-1RP3 antibody, IL1F5 antibody, IL1HY1 antibody, IL1L1 antibody, IL1RP3 antibody, IL36RA antibody, IL36RN antibody, Interleukin 1 delta antibody, Interleukin 1 family member 5 (delta) antibody, Interleukin 1 family member 5 antibody, Interleukin 1 HY1 antibody, Interleukin 1 like protein 1 antibody, Interleukin 1 receptor antagonist homolog 1 antibody, Interleukin 36 receptor antagonist antibody, Interleukin-1 delta antibody, Interleukin-1 family member 5 antibody, Interleukin-1 HY1 antibody, Interleukin-1 receptor antagonist homolog 1 antibody, Interleukin-1-like protein 1 antibody, Interleukin-36 receptor antagonist protein antibody, MGC29840 antibody, PSORP antibody, RP23-176J12.6 antibody

UniProt: Q9UBH0