IL23A antibody (AA 20-155) (HRP)

Catalog No. ABIN7156871

Product Details anti-IL23A Antibody (HRP)

Target: IL23A (Interleukin 23, alpha subunit p19 (IL23A))

Binding Specificity: AA 20-155

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IL23A antibody is conjugated to HRP

Application: ELISA

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Interleukin-23 subunit alpha protein (20-155AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for IL23A

Target: IL23A (Interleukin 23, alpha subunit p19 (IL23A))

Alternative Name: IL23A (IL23A Products)

Background:

Background: Associates with IL12B to form the IL-23 interleukin, a heterodimeric cytokine which functions in innate and adaptive immunity. IL-23 may constitute with IL-17 an acute response to infection in peripheral tissues. IL-23 binds to a heterodimeric receptor complex composed of IL12RB1 and IL23R, activates the Jak-Stat signaling cascade, stimulates memory rather than naive T-cells and promotes production of proinflammatory cytokines. IL-23 induces autoimmune inflammation and thus may be responsible for autoimmune inflammatory diseases and may be important for tumorigenesis.

Aliases: IL 23 A antibody, IL 23 antibody, IL 23 subunit alpha antibody, IL 23A antibody, IL 23p19 antibody, IL-23 subunit alpha antibody, IL-23-A antibody, IL-23p19 antibody, IL12B antibody, IL23 antibody, Il23a antibody, IL23A_HUMAN antibody, IL23P19 antibody, interleukin 12B antibody, Interleukin 23 alpha subunit p19 antibody, Interleukin 23 p19 subunit antibody, interleukin 23 subunit alpha antibody, interleukin 23 subunit p19 antibody, interleukin six, G CSF related factor antibody, Interleukin-23 subunit alpha antibody, Interleukin-23 subunit p19 antibody, JKA3 induced upon T cell activation antibody, MGC79388 antibody, P19 antibody, SGRF antibody

UniProt: Q9NPF7

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation