IL22 Receptor alpha 1 antibody (AA 250-573)

Catalog No. ABIN7156855

Product Details anti-IL22 Receptor alpha 1 Antibody

Target: IL22 Receptor alpha 1 (IL22RA1) (Interleukin 22 Receptor, alpha 1 (IL22RA1))

Binding Specificity: AA 250-573

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IL22 Receptor alpha 1 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Interleukin-22 receptor subunit alpha-1 protein (250-573AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: IHC:1:20-1:200, IF:1:50-1:500,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for IL22 Receptor alpha 1

Target: IL22 Receptor alpha 1 (IL22RA1) (Interleukin 22 Receptor, alpha 1 (IL22RA1))

Alternative Name: IL22RA1 (IL22RA1 Products)

Synonyms: IL22RA1 antibody, CRF2-9 antibody, IL22R antibody, IL22R1 antibody, 9130219A07Rik antibody, ENSMUSG00000073746 antibody, IL-22R antibody, Il22r antibody, RGD1559655 antibody, interleukin 22 receptor subunit alpha 1 antibody, interleukin 22 receptor, alpha 1 antibody, IL22RA1 antibody, Il22ra1 antibody

Background:

Background: Component of the receptor for IL20, IL22 and IL24. Component of IL22 receptor formed by IL22RA1 and IL10RB enabling IL22 signaling via JAK/STAT pathways. IL22 also induces activation of MAPK1/MAPK3 and Akt kinases pathways. Component of one of the receptor for IL20 and IL24 formed by IL22RA1 and IL20RB also signaling through STATs activation. Mediates IL24 antiangiogenic activity as well as IL24 inhibitory effect on endothelial cell tube formation and differentiation.

Aliases: CRF2 9 antibody, CRF2-9 antibody, Cytokine receptor class-II member 9 antibody, cytokine receptor classII member 9 antibody, Cytokine receptor family 2 member 9 antibody, I22R1_HUMAN antibody, IL-22 receptor subunit alpha-1 antibody, IL-22R-alpha-1 antibody, IL-22RA1 antibody, IL22 Receptor Alpha antibody, IL22R antibody, IL22R1 antibody, Il22ra1 antibody, ILTIF R1 chain antibody, Interleukin 22 Receptor alpha 1 antibody, Interleukin 22 Receptor antibody, Interleukin-22 receptor subunit alpha-1 antibody, ZcytoR11 antibody

UniProt: Q8N6P7