IL17RA antibody (AA 552-743)

Catalog No. ABIN7156803

Product Details anti-IL17RA Antibody

Target: IL17RA (Interleukin 17 Receptor A (IL17RA))

Binding Specificity: AA 552-743

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IL17RA antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Cross-Reactivity: Human, Mouse

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Interleukin-17 receptor A protein (552-743AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: WB:1:500-1:5000, IF:1:50-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for IL17RA

Target: IL17RA (Interleukin 17 Receptor A (IL17RA))

Alternative Name: IL17RA (IL17RA Products)

Synonyms: IL17R antibody, CANDF5 antibody, CD217 antibody, CDw217 antibody, IL-17RA antibody, hIL-17R antibody, Il17r antibody, AW538159 antibody, Cdw217 antibody, VDw217 antibody, interleukin 17 receptor A antibody, IL17RA antibody, Il17ra antibody

Background:

Background: Receptor for IL17A (PubMed:17911633, PubMed:9367539). Receptor for IL17F (PubMed:19838198, PubMed:17911633). Binds to IL17A with higher affinity than to IL17F (PubMed:17911633). Binds IL17A and IL17F homodimers as part of a heterodimeric complex with IL17RC (PubMed:16785495). Also binds heterodimers formed by IL17A and IL17F as part of a heterodimeric complex with IL17RC (PubMed:18684971). Receptor for IL17C as part of a heterodimeric complex with IL17RE (PubMed:21993848). Activation of IL17RA leads to induction of expression of inflammatory chemokines and cytokines such as CXCL1, CXCL8/IL8 and IL6 (PubMed:16785495, PubMed:17911633, PubMed:18684971).

Aliases: CANDF5 antibody, CD217 antibody, CD217 antigen antibody, CDw217 antibody, CTLA8 antibody, HIL 17R antibody, hIL17R antibody, I17RA_HUMAN antibody, IL 17 receptor A antibody, IL 17 receptor antibody, IL 17RA antibody, IL-17 receptor A antibody, IL-17RA antibody, IL17 antibody, IL17A receptor antibody, IL17R antibody, IL17RA antibody, IMD51 antibody, Interleukin 17 receptor A antibody, Interleukin-17 receptor A antibody, MGC10262 antibody

UniProt: Q96F46

Pathways: SARS-CoV-2 Protein Interactome