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IFIT2 antibody (AA 130-265)

IFIT2 Reactivity: Human WB, ELISA, IHC, IF Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7156667
  • Target See all IFIT2 Antibodies
    IFIT2 (Interferon-Induced Protein with Tetratricopeptide Repeats 2 (IFIT2))
    Binding Specificity
    • 15
    • 7
    • 7
    • 6
    • 6
    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 130-265
    Reactivity
    • 45
    • 2
    • 1
    • 1
    Human
    Host
    • 43
    • 2
    Rabbit
    Clonality
    • 45
    Polyclonal
    Conjugate
    • 17
    • 5
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This IFIT2 antibody is un-conjugated
    Application
    • 26
    • 23
    • 13
    • 13
    • 5
    • 4
    • 3
    • 3
    • 3
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
    Cross-Reactivity
    Human, Rat
    Purification
    >95%, Protein G purified
    Immunogen
    Recombinant Human Interferon-induced protein with tetratricopeptide repeats 2 protein (130-265AA)
    Isotype
    IgG
  • Application Notes
    Recommended dilution: WB:1:500-1:5000, IHC:1:500-1:1000, IF:1:50-1:200,
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C,-80 °C
    Storage Comment
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target
    IFIT2 (Interferon-Induced Protein with Tetratricopeptide Repeats 2 (IFIT2))
    Alternative Name
    IFIT2 (IFIT2 Products)
    Synonyms
    G10P2 antibody, GARG-39 antibody, IFI-54 antibody, IFI-54K antibody, IFI54 antibody, IFIT-2 antibody, ISG-54 K antibody, ISG-54K antibody, ISG54 antibody, P54 antibody, cig42 antibody, wu:fb58d07 antibody, DKFZp468G198 antibody, AV302338 antibody, Ifi54 antibody, interferon induced protein with tetratricopeptide repeats 2 antibody, interferon-induced protein with tetratricopeptide repeats 2 antibody, interferon-induced protein with tetratricopeptide repeats 15 antibody, IFIT2 antibody, Ifit2 antibody, ifit15 antibody
    Background

    Background: IFN-induced antiviral protein which inhibits expression of viral messenger RNAs lacking 2\\\'-O-methylation of the 5\\\' cap. The ribose 2\\\'-O-methylation would provide a molecular signature to distinguish between self and non-self mRNAs by the host during viral infection. Viruses evolved several ways to evade this restriction system such as encoding their own 2\\\'-O-methylase for their mRNAs or by stealing host cap containing the 2\\\'-O-methylation (cap snatching mechanism). Binds AU-rich viral RNAs, with or without 5\\\' triphosphorylation, RNA-binding is required for antiviral activity. Can promote apoptosis.

    Aliases: CIG-42 antibody, cig42 antibody, G10P2 antibody, GARG 39 antibody, Glucocorticoid attenuated response gene 39 antibody, IFI 54 antibody, IFI 54K antibody, IFI-54K antibody, IFI54 antibody, IFIT 2 antibody, IFIT-2 antibody, IFIT2 antibody, IFIT2_HUMAN antibody, Interferon induced 54 kDa protein antibody, Interferon induced protein 54 antibody, Interferon induced protein with tetratricopeptide repeats 2 antibody, Interferon, alpha inducible protein (MW 54kD) antibody, Interferon-induced 54 kDa protein antibody, Interferon-induced protein with tetratricopeptide repeats 2 antibody, ISG 54 K antibody, ISG 54K antibody, ISG-54 K antibody, ISG54 antibody

    UniProt
    P09913
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