IL29 antibody (AA 21-200)

Catalog No. ABIN7156608

Product Details anti-IL29 Antibody

Target: IL29 (Interleukin 29 (IL29))

Binding Specificity: AA 21-200

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IL29 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Interferon lambda-1 protein (21-200AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: IHC:1:20-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for IL29

Target: IL29 (Interleukin 29 (IL29))

Alternative Name: IFNL1 (IL29 Products)

Synonyms: IL-29 antibody, IL29 antibody, interferon lambda 1 antibody, interferon lambda-1 antibody, interleukin 29 (interferon, lambda 1) antibody, IFNL1 antibody, LOC612539 antibody, IL29 antibody

Background:

Background: Cytokine with antiviral, antitumour and immunomodulatory activities. Plays a critical role in the antiviral host defense, predominantly in the epithelial tissues. Acts as a ligand for the heterodimeric class II cytokine receptor composed of IL10RB and IFNLR1, and receptor engagement leads to the activation of the JAK/STAT signaling pathway resulting in the expression of IFN-stimulated genes (ISG), which mediate the antiviral state. Has a restricted receptor distribution and therefore restricted targets: is primarily active in epithelial cells and this cell type-selective action is because of the epithelial cell-specific expression of its receptor IFNLR1. Exerts an immunomodulatory effect by up-regulating MHC class I antigen expression.

Aliases: IFNL1 antibody, IL29 antibody, ZCYTO21Interferon lambda-1 antibody, IFN-lambda-1 antibody, Cytokine Zcyto21 antibody, Interleukin-29 antibody, IL-29 antibody

UniProt: Q8IU54