IFNAR2 antibody (AA 27-243)

Catalog No. ABIN7156578

Product Details anti-IFNAR2 Antibody

Target: IFNAR2 (Interferon alpha/beta Receptor 2 (IFNAR2))

Binding Specificity: AA 27-243

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IFNAR2 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Interferon alpha/beta receptor 2 protein (27-243AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: IHC:1:20-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for IFNAR2

Target: IFNAR2 (Interferon alpha/beta Receptor 2 (IFNAR2))

Alternative Name: IFNAR2 (IFNAR2 Products)

Synonyms: AI747302 antibody, Ifnar-2 antibody, IFN-R antibody, IFN-alpha-REC antibody, IFNABR antibody, IFNARB antibody, IFN-R-2 antibody, IFNBR antibody, interferon alpha and beta receptor subunit 2 antibody, interferon (alpha and beta) receptor 2 antibody, IFNAR2 antibody, Ifnar2 antibody

Background:

Background: Associates with IFNAR1 to form the type I interferon receptor. Receptor for interferons alpha and beta. Involved in IFN-mediated STAT1, STAT2 and STAT3 activation. Isoform 1 and isoform 2 are directly involved in signal transduction due to their association with the TYR kinase, JAK1. Isoform 3 is a potent inhibitor of type I IFN receptor activity.

Aliases: Human interferon alpha/beta receptor antibody, IFN alpha REC antibody, IFN R antibody, IFN-a/R2 antibody, IFN-a/R antibody, IFN-alpha binding protein antibody, IFN-alpha/beta receptor 2 antibody, IFN-R-2 antibody, IFNABR antibody, IFNAR2 antibody, IFNARB antibody, IFNR antibody, INAR2_HUMAN antibody, Interferon (alpha beta and omega) receptor 2 antibody, Interferon alpha binding protein antibody, Interferon alpha/beta receptor 2 antibody, Interferon alpha/beta receptor beta chain antibody, Type I interferon receptor 2 antibody, Type I interferon receptor antibody

UniProt: P48551

Pathways: JAK-STAT Signaling, Hepatitis C