ITGB6 antibody (AA 451-586) (Biotin)

Catalog No. ABIN7156495

Product Details anti-ITGB6 Antibody (Biotin)

Target: ITGB6 (Integrin beta-6 (ITGB6))

Binding Specificity: AA 451-586

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ITGB6 antibody is conjugated to Biotin

Application: ELISA

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Integrin beta-6 protein (451-586AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for ITGB6

Target: ITGB6 (Integrin beta-6 (ITGB6))

Alternative Name: ITGB6 (ITGB6 Products)

Synonyms: 2210409C20Rik antibody, 4831415H04Rik antibody, ITB6 antibody, integrin subunit beta 6 antibody, integrin beta 6 antibody, ITGB6 antibody, Itgb6 antibody

Background:

Background: Integrin alpha-V/beta-6 is a receptor for fibronectin and cytotactin. It recognizes the sequence R-G-D in its ligands. Internalisation of integrin alpha-V/beta-6 via clathrin-mediated endocytosis promotes carcinoma cell invasion. ITGAV:ITGB6 acts as a receptor for fibrillin-1 (FBN1) and mediates R-G-D-dependent cell adhesion to FBN1 (PubMed:17158881).

Aliases: Integrin beta-6 antibody, ITB6_HUMAN antibody, ITGB6 antibody

UniProt: P18564