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Integrin Alpha2b antibody (AA 639-887)

CD41 Reactivity: Human ELISA, IHC, IF Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7156456
  • Target See all Integrin Alpha2b (CD41) Antibodies
    Integrin Alpha2b (CD41)
    Binding Specificity
    • 16
    • 4
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 639-887
    Reactivity
    • 120
    • 32
    • 21
    • 8
    • 7
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 75
    • 47
    • 23
    Rabbit
    Clonality
    • 97
    • 42
    • 1
    Polyclonal
    Conjugate
    • 59
    • 16
    • 14
    • 12
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Integrin Alpha2b antibody is un-conjugated
    Application
    • 102
    • 42
    • 27
    • 26
    • 20
    • 19
    • 13
    • 13
    • 9
    • 9
    • 8
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
    Cross-Reactivity
    Human
    Purification
    >95%, Protein G purified
    Immunogen
    Recombinant Human Integrin alpha-IIb protein (639-887AA)
    Isotype
    IgG
    Top Product
    Discover our top product CD41 Primary Antibody
  • Application Notes
    Recommended dilution: IHC:1:20-1:200, IF:1:200-1:500,
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C,-80 °C
    Storage Comment
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target
    Integrin Alpha2b (CD41)
    Alternative Name
    ITGA2B (CD41 Products)
    Background

    Background: Integrin alpha-IIb/beta-3 is a receptor for fibronectin, fibrinogen, plasminogen, prothrombin, thrombospondin and vitronectin. It recognizes the sequence R-G-D in a wide array of ligands. It recognizes the sequence H-H-L-G-G-G-A-K-Q-A-G-D-V in fibrinogen gamma chain. Following activation integrin alpha-IIb/beta-3 brings about platelet/platelet interaction through binding of soluble fibrinogen. This step leads to rapid platelet aggregation which physically plugs ruptured endothelial cell surface.

    Aliases: antigen CD41 antibody, BDPLT16 antibody, BDPLT2 antibody, CD41 antibody, CD41B antibody, form 2 antibody, GP2B antibody, GPalpha IIb antibody, GPIIb antibody, GT antibody, GTA antibody, HPA3 antibody, Integrin alpha 2b antibody, Integrin alpha IIb antibody, Integrin alpha-IIb light chain antibody, Integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41) antibody, ITA2B_HUMAN antibody, Itga2b antibody, ITGAB antibody, platelet fibrinogen receptor, alpha subunit antibody, platelet glycoprotein IIb of IIb/IIIa complex antibody, Platelet membrane glycoprotein IIb antibody, platelet specific antigen BAK antibody, PPP1R93 antibody

    UniProt
    P08514
    Pathways
    Integrin Complex
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