Integrin Alpha2b antibody (AA 639-887)
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- Target See all Integrin Alpha2b (CD41) Antibodies
- Integrin Alpha2b (CD41)
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Binding Specificity
- AA 639-887
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This Integrin Alpha2b antibody is un-conjugated
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Application
- ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
- Cross-Reactivity
- Human
- Purification
- >95%, Protein G purified
- Immunogen
- Recombinant Human Integrin alpha-IIb protein (639-887AA)
- Isotype
- IgG
- Top Product
- Discover our top product CD41 Primary Antibody
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- Application Notes
- Recommended dilution: IHC:1:20-1:200, IF:1:200-1:500,
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 - Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Target
- Integrin Alpha2b (CD41)
- Alternative Name
- ITGA2B (CD41 Products)
- Background
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Background: Integrin alpha-IIb/beta-3 is a receptor for fibronectin, fibrinogen, plasminogen, prothrombin, thrombospondin and vitronectin. It recognizes the sequence R-G-D in a wide array of ligands. It recognizes the sequence H-H-L-G-G-G-A-K-Q-A-G-D-V in fibrinogen gamma chain. Following activation integrin alpha-IIb/beta-3 brings about platelet/platelet interaction through binding of soluble fibrinogen. This step leads to rapid platelet aggregation which physically plugs ruptured endothelial cell surface.
Aliases: antigen CD41 antibody, BDPLT16 antibody, BDPLT2 antibody, CD41 antibody, CD41B antibody, form 2 antibody, GP2B antibody, GPalpha IIb antibody, GPIIb antibody, GT antibody, GTA antibody, HPA3 antibody, Integrin alpha 2b antibody, Integrin alpha IIb antibody, Integrin alpha-IIb light chain antibody, Integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41) antibody, ITA2B_HUMAN antibody, Itga2b antibody, ITGAB antibody, platelet fibrinogen receptor, alpha subunit antibody, platelet glycoprotein IIb of IIb/IIIa complex antibody, Platelet membrane glycoprotein IIb antibody, platelet specific antigen BAK antibody, PPP1R93 antibody
- UniProt
- P08514
- Pathways
- Integrin Complex
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