ITGA2 antibody (AA 188-365)

Catalog No. ABIN7156430

Product Details anti-ITGA2 Antibody

Target: ITGA2 (Integrin alpha 2 (ITGA2))

Binding Specificity: AA 188-365

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ITGA2 antibody is un-conjugated

Application: Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Integrin alpha-2 protein (188-365AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: IHC:1:20-1:200, IF:1:50-1:500,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for ITGA2

Target: ITGA2 (Integrin alpha 2 (ITGA2))

Alternative Name: ITGA2 (ITGA2 Products)

Synonyms: BR antibody, CD49B antibody, GPIa antibody, HPA-5 antibody, VLA-2 antibody, VLAA2 antibody, DX5 antibody, integrin subunit alpha 2 antibody, integrin alpha 2 antibody, ITGA2 antibody, Itga2 antibody

Background:

Background: Integrin alpha-2/beta-1 is a receptor for laminin, collagen, collagen C-propeptides, fibronectin and E-cadherin. It recognizes the proline-hydroxylated sequence G-F-P-G-E-R in collagen. It is responsible for adhesion of platelets and other cells to collagens, modulation of collagen and collagenase gene expression, force generation and organization of newly synthesized extracellular matrix.

Aliases: BR antibody, CD 49b antibody, CD49 antigen like family member B antibody, CD49 antigen-like family member B antibody, CD49b antibody, CD49b antigen antibody, Collagen receptor antibody, DX5 antibody, Glycoprotein Ia deficiency included antibody, GP Ia antibody, GP Ia deficiency, included antibody, GPIa antibody, HPA 5 included antibody, HPA5 included antibody, Human platelet alloantigen system 5 antibody, Integrin alpha 2 antibody, Integrin alpha II antibody, Integrin alpha-2 antibody, Integrin, alpha 2 (CD49B alpha 2 subunit of VLA 2 receptor) antibody, ITA2_HUMAN antibody, ITGA2 antibody, Platelet alloantigen Br(a), included antibody, Platelet antigen Br antibody, Platelet glycoprotein GPIa antibody, Platelet glycoprotein Ia antibody, Platelet glycoprotein Ia/IIa antibody, Platelet membrane glycoprotein Ia antibody, Platelet receptor for collagen, deficiency of, included antibody, Very late activation protein 2 receptor alpha 2 subunit antibody, VLA 2 alpha chain antibody, VLA 2 antibody, VLA 2 subunit alpha antibody, VLA-2 subunit alpha antibody, VLA2 antibody, VLA2 receptor alpha 2 subunit antibody, VLAA2 antibody

UniProt: P17301

Pathways: CXCR4-mediated Signaling Events, Smooth Muscle Cell Migration, Integrin Complex