OCRL antibody (AA 121-271)

Catalog No. ABIN7156316

Product Details anti-OCRL Antibody

Target: OCRL (Oculocerebrorenal Syndrome of Lowe (OCRL))

Binding Specificity: AA 121-271

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This OCRL antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Inositol polyphosphate 5-phosphatase OCRL-1 protein (121-271AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: IHC:1:200-1:500,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for OCRL

Target: OCRL (Oculocerebrorenal Syndrome of Lowe (OCRL))

Alternative Name: OCRL (OCRL Products)

Synonyms: OCRL antibody, wu:fi09g03 antibody, zgc:152864 antibody, locr antibody, nphl2 antibody, ocrl1 antibody, inpp5f antibody, INPP5F antibody, LOCR antibody, NPHL2 antibody, OCRL-1 antibody, OCRL1 antibody, 9530014D17Rik antibody, BB143339 antibody, OCRL, inositol polyphosphate-5-phosphatase antibody, phosphatidylinositol polyphosphate 5-phosphatase antibody, oculocerebrorenal syndrome of Lowe antibody, Ocrl antibody, NAEGRDRAFT_58601 antibody, OCRL antibody, ocrl antibody

Background:

Background: Converts phosphatidylinositol 4,5-bisphosphate to phosphatidylinositol 4-phosphate. Also converts inositol 1,4,5-trisphosphate to inositol 1,4-bisphosphate and inositol 1,3,4,5-tetrakisphosphate to inositol 1,3,4-trisphosphate (PubMed:25869668, PubMed:7761412, PubMed:9430698). May function in lysosomal membrane trafficking by regulating the specific pool of phosphatidylinositol 4,5-bisphosphate that is associated with lysosomes. Involved in primary cilia assembly (PubMed:22228094, PubMed:22543976).

Aliases: EC 3.1.3.36 antibody, Inositol polyphosphate 5 phosphatase OCRL 1 antibody, Inositol polyphosphate 5 phosphatase OCRL1 antibody, Inositol polyphosphate 5-phosphatase OCRL-1 antibody, INPP5F antibody, LOCR antibody, Lowe oculocerebrorenal syndrome protein antibody, NPHL2 antibody, OCRL 1 antibody, OCRL antibody, OCRL_HUMAN antibody, OCRL1 antibody, Oculocerebrorenal syndrome of Lowe antibody, Phosphatidylinositol polyphosphate 5 phosphatase antibody

UniProt: Q01968

Pathways: Inositol Metabolic Process