Plexin B2 antibody (AA 1458-1673)

Catalog No. ABIN7156267

Product Details anti-Plexin B2 Antibody

Target: Plexin B2 (PLXNB2)

Binding Specificity: AA 1458-1673

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Plexin B2 antibody is un-conjugated

Application: ELISA, Western Blotting (WB)

Cross-Reactivity: Human

Purification: >95%, Antigen Affinity purified & Affinity purified

Immunogen: Recombinant Human Inhibitor of nuclear factor kappa-B kinase-interacting protein (1458-1673AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: WB:1:500-1:2000,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for Plexin B2

Target: Plexin B2 (PLXNB2)

Alternative Name: PLXNB2 (PLXNB2 Products)

Background:

Background: Cell surface receptor for SEMA4C, SEMA4D and SEMA4G that plays an important role in cell-cell signaling. Binding to class 4 semaphorins promotes downstream activation of RHOA and phosphorylation of ERBB2 at \'Tyr-1248\'. Required for normal differentiation and migration of neuronal cells during brain corticogenesis and for normal embryonic brain development. Regulates the migration of cerebellar granule cells in the developing brain. Plays a role in RHOA activation and subsequent changes of the actin cytoskeleton. Plays a role in axon guidance, invasive growth and cell migration. May modulate the activity of RAC1 and CDC42. Down-regulates macrophage migration in wound-healing assays (in vitro) (By similarity).

Aliases: PLXNB2 antibody, KIAA0315 antibody, Plexin-B2 antibody, MM1 antibody

UniProt: O15031

Pathways: Tube Formation