ING4 antibody (AA 75-249)
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- Target See all ING4 Antibodies
- ING4 (Inhibitor of Growth Family, Member 4 (ING4))
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Binding Specificity
- AA 75-249
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This ING4 antibody is un-conjugated
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Application
- ELISA, Immunohistochemistry (IHC)
- Cross-Reactivity
- Human
- Purification
- >95%, Protein G purified
- Immunogen
- Recombinant Human Inhibitor of growth protein 4 protein (75-249AA)
- Isotype
- IgG
- Top Product
- Discover our top product ING4 Primary Antibody
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- Application Notes
- Recommended dilution: IHC:1:20-1:200,
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 - Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Target
- ING4 (Inhibitor of Growth Family, Member 4 (ING4))
- Alternative Name
- ING4 (ING4 Products)
- Synonyms
- wu:fb11d09 antibody, wu:fb50e02 antibody, zgc:110619 antibody, ING4 antibody, my036 antibody, p29ING4 antibody, D6Wsu147e antibody, D6Xrf92 antibody, inhibitor of growth family, member 4 antibody, inhibitor of growth family member 4 antibody, ing4 antibody, ING4 antibody, Ing4 antibody
- Background
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Background: Component of the HBO1 complex which has a histone H4-specific acetyltransferase activity, a reduced activity toward histone H3 and is responsible for the bulk of histone H4 acetylation in vivo. Through chromatin acetylation it may function in DNA replication. May inhibit tumor progression by modulating the transcriptional output of signaling pathways which regulate cell proliferation. Can suppress brain tumor angiogenesis through transcriptional repression of RELA/NFKB3 target genes when complexed with RELA. May also specifically suppress loss of contact inhibition elicited by activated oncogenes such as MYC. Represses hypoxia inducible factor\'s (HIF) activity by interacting with HIF prolyl hydroxylase 2 (EGLN1). Can enhance aopotosis induced by serum starvation in mammary epithelial cell line HC11 (By similarity).
Aliases: Brain my036 protein antibody, Candidate tumor suppressor p33 ING 1 homolog antibody, Candidate tumor suppressor p33 ING1 homolog antibody, D6Wsu147e antibody, D6Xrf92 antibody, ING 1 like protein antibody, ING 4 antibody, ING1 like protein antibody, ING4 antibody, ING4_HUMAN antibody, Inhibitor of growth family member 4 antibody, Inhibitor of growth family member 4 long isoform antibody, Inhibitor of growth protein 4 antibody, MGC12557 antibody, my036 antibody, p29 ING 4 antibody, p29 ING4 antibody, p29ING4 antibody
- UniProt
- Q9UNL4
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