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KPNA4 antibody (AA 51-239) (Biotin)

KPNA4 Reactivity: Human ELISA Host: Rabbit Polyclonal Biotin
Catalog No. ABIN7156123
  • Target See all KPNA4 Antibodies
    KPNA4 (Karyopherin (Importin) alpha 4 (KPNA4))
    Binding Specificity
    • 15
    • 7
    • 6
    • 5
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 51-239
    Reactivity
    • 42
    • 36
    • 15
    • 5
    • 4
    • 4
    • 4
    • 4
    • 1
    • 1
    • 1
    Human
    Host
    • 50
    • 1
    • 1
    Rabbit
    Clonality
    • 51
    • 1
    Polyclonal
    Conjugate
    • 23
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This KPNA4 antibody is conjugated to Biotin
    Application
    • 40
    • 19
    • 14
    • 13
    • 11
    • 9
    • 7
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    ELISA
    Cross-Reactivity
    Human
    Purification
    >95%, Protein G purified
    Immunogen
    Recombinant Human Importin subunit alpha-3 protein (51-239AA)
    Isotype
    IgG
    Top Product
    Discover our top product KPNA4 Primary Antibody
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C,-80 °C
    Storage Comment
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target
    KPNA4 (Karyopherin (Importin) alpha 4 (KPNA4))
    Alternative Name
    KPNA4 (KPNA4 Products)
    Synonyms
    IPOA3 antibody, QIP1 antibody, SRP3 antibody, 6 antibody, ATIMPALPHA3 antibody, IMPA-3 antibody, IMPORTIN ALPHA 3 antibody, IMPORTIN ALPHA ISOFORM 3 antibody, MODIFIER OF SNC1 antibody, T10M13.16 antibody, T10M13_16 antibody, LOC100224013 antibody, 1110058D08Rik antibody, importin antibody, ipoa3 antibody, qip1 antibody, srp3 antibody, impa3 antibody, wu:fa56d07 antibody, wu:fa66g10 antibody, wu:fe14c04 antibody, wu:fi04h11 antibody, wu:fi19b05 antibody, karyopherin subunit alpha 4 antibody, ARM repeat superfamily protein antibody, importin alpha 3 antibody, karyopherin (importin) alpha 4 antibody, karyopherin alpha 4 (importin alpha 3) S homeolog antibody, karyopherin alpha 4 (importin alpha 3) antibody, KPNA4 antibody, MOS6 antibody, LOC100533341 antibody, Kpna4 antibody, kpna4.S antibody, kpna4 antibody
    Background

    Background: Functions in nuclear protein import as an adapter protein for nuclear receptor KPNB1. Binds specifically and directly to substrates containing either a simple or bipartite NLS motif. Docking of the importin/substrate complex to the nuclear pore complex (NPC) is mediated by KPNB1 through binding to nucleoporin FxFG repeats and the complex is subsequently translocated through the pore by an energy requiring, Ran-dependent mechanism. At the nucleoplasmic side of the NPC, Ran binds to importin-beta and the three components separate and importin-alpha and -beta are re-exported from the nucleus to the cytoplasm where GTP hydrolysis releases Ran from importin. The directionality of nuclear import is thought to be conferred by an asymmetric distribution of the GTP- and GDP-bound forms of Ran between the cytoplasm and nucleus. In vitro, mediates the nuclear import of human cytomegalovirus UL84 by recognizing a non-classical NLS. In vitro, mediates the nuclear import of human cytomegalovirus UL84 by recognizing a non-classical NLS.

    Aliases: FLJ31113 antibody, IMA3_HUMAN antibody, Importin alpha 3 antibody, Importin alpha 4 subunit antibody, Importin alpha Q1 antibody, Importin subunit alpha 3 antibody, Importin subunit alpha-3 antibody, IPO A3 antibody, IPOA 3 antibody, IPOA3 antibody, Karyopherin alpha 4 (importin alpha 3) antibody, Karyopherin alpha 4 antibody, Karyopherin alpha 4 importin alpha 3 antibody, Karyopherin alpha 4 subunit antibody, Karyopherin subunit alpha 4 antibody, Karyopherin subunit alpha-4 antibody, KPNA 4 antibody, Kpna4 antibody, MGC12217 antibody, MGC26703 antibody, OTTHUMP00000213880 antibody, QIP 1 antibody, Qip1 antibody, Qip1 protein antibody, SRP 3 antibody, SRP3 antibody

    UniProt
    O00629
    Pathways
    Protein targeting to Nucleus
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