HYAL3 antibody (AA 198-417)

Catalog No. ABIN7155973

Product Details anti-HYAL3 Antibody

Target: HYAL3 (Hyaluronidase-3 (HYAL3))

Binding Specificity: AA 198-417

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HYAL3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Cross-Reactivity: Human, Mouse

Purification: Antigen Affinity Purified

Immunogen: Recombinant Human Hyaluronidase-3 protein (198-417AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: WB:1:200-1:1000, IHC:1:20-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for HYAL3

Target: HYAL3 (Hyaluronidase-3 (HYAL3))

Alternative Name: HYAL3 (HYAL3 Products)

Synonyms: HYAL1 antibody, HYAL3 antibody, Hyal-3 antibody, HYAL-3 antibody, LUCA-3 antibody, LUCA3 antibody, Hyl3 antibody, hyaluronoglucosaminidase 3 antibody, HYAL3 antibody, Hyal3 antibody

Background:

Background: This gene encodes a member of the hyaluronidase family. Hyaluronidases are endoglycosidase enzymes that degrade hyaluronan, one of the major glycosaminoglycans of the extracellular matrix. The regulated turnover of hyaluronan plays a critical role in many biological processes including cell proliferation, migration and differentiation. The encoded protein may also play an important role in sperm function. This gene is one of several related genes in a region of chromosome 3p21.3 associated with tumor suppression, and the expression of specific transcript variants may be indicative of tumor status. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and some isoforms may lack hyaluronidase activity. This gene overlaps and is on the same strand as N-acetyltransferase 6 (GCN5-related), and some transcripts of each gene share a portion of the first exon.

Aliases: Hyal-3 antibody, HYAL3 antibody, HYAL3_HUMAN antibody, Hyaluronidase 3 antibody, Hyaluronidase-3 antibody, Hyaluronoglucosaminidase 3 antibody, Hyaluronoglucosaminidase-3 antibody, LUCA-3 antibody, LUCA14 antibody, LUCA3 antibody, Lung carcinoma protein 3 antibody, Minna14 antibody

UniProt: O43820

Pathways: Glycosaminoglycan Metabolic Process