HORMAD2 antibody (AA 14-307) (Biotin)
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- Target See all HORMAD2 Antibodies
- HORMAD2 (HORMA Domain Containing 2 (HORMAD2))
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Binding Specificity
- AA 14-307
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This HORMAD2 antibody is conjugated to Biotin
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Application
- ELISA
- Cross-Reactivity
- Human
- Purification
- >95%, Protein G purified
- Immunogen
- Recombinant Human HORMA domain-containing protein 2 protein (14-307AA)
- Isotype
- IgG
- Top Product
- Discover our top product HORMAD2 Primary Antibody
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 - Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Target
- HORMAD2 (HORMA Domain Containing 2 (HORMAD2))
- Alternative Name
- HORMAD2 (HORMAD2 Products)
- Synonyms
- 4930529M09Rik antibody, HORMA domain containing 2 antibody, HORMAD2 antibody, Hormad2 antibody
- Background
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Background: Essential for synapsis surveillance during meiotic prophase via the recruitment of ATR activity. Plays a key role in the male mid-pachytene checkpoint and the female meiotic prophase checkpoint: required for efficient build-up of ATR activity on unsynapsed chromosome regions, a process believed to form the basis of meiotic silencing of unsynapsed chromatin (MSUC) and meiotic prophase quality control in both sexes. Required for the DNA double-strand break-independent, BRCA1-dependent activation of ATR on the sex chromosomes that is essential for normal sex body formation.
Aliases: 4930529M09Rik antibody, CT46.2 antibody, HORM2_HUMAN antibody, HORMA domain containing 2 antibody, HORMA domain-containing protein 2 antibody, Hormad2 antibody, MGC26710 antibody, RP23-329P17.4 antibody
- UniProt
- Q8N7B1
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