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HORMAD2 antibody (AA 14-307) (Biotin)

HORMAD2 Reactivity: Human ELISA Host: Rabbit Polyclonal Biotin
Catalog No. ABIN7155902
  • Target See all HORMAD2 Antibodies
    HORMAD2 (HORMA Domain Containing 2 (HORMAD2))
    Binding Specificity
    • 4
    • 2
    • 2
    • 1
    • 1
    AA 14-307
    Reactivity
    • 16
    • 5
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    Human
    Host
    • 14
    • 2
    Rabbit
    Clonality
    • 15
    • 1
    Polyclonal
    Conjugate
    • 13
    • 2
    • 1
    This HORMAD2 antibody is conjugated to Biotin
    Application
    • 10
    • 7
    • 3
    ELISA
    Cross-Reactivity
    Human
    Purification
    >95%, Protein G purified
    Immunogen
    Recombinant Human HORMA domain-containing protein 2 protein (14-307AA)
    Isotype
    IgG
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    Discover our top product HORMAD2 Primary Antibody
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C,-80 °C
    Storage Comment
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target
    HORMAD2 (HORMA Domain Containing 2 (HORMAD2))
    Alternative Name
    HORMAD2 (HORMAD2 Products)
    Synonyms
    4930529M09Rik antibody, HORMA domain containing 2 antibody, HORMAD2 antibody, Hormad2 antibody
    Background

    Background: Essential for synapsis surveillance during meiotic prophase via the recruitment of ATR activity. Plays a key role in the male mid-pachytene checkpoint and the female meiotic prophase checkpoint: required for efficient build-up of ATR activity on unsynapsed chromosome regions, a process believed to form the basis of meiotic silencing of unsynapsed chromatin (MSUC) and meiotic prophase quality control in both sexes. Required for the DNA double-strand break-independent, BRCA1-dependent activation of ATR on the sex chromosomes that is essential for normal sex body formation.

    Aliases: 4930529M09Rik antibody, CT46.2 antibody, HORM2_HUMAN antibody, HORMA domain containing 2 antibody, HORMA domain-containing protein 2 antibody, Hormad2 antibody, MGC26710 antibody, RP23-329P17.4 antibody

    UniProt
    Q8N7B1
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