HOPX antibody (AA 1-73)

Catalog No. ABIN7155873

Product Details anti-HOPX Antibody

Target: HOPX (HOP Homeobox (HOPX))

Binding Specificity: AA 1-73

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HOPX antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Homeodomain-only protein (1-73AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: IHC:1:20-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for HOPX

Target: HOPX (HOP Homeobox (HOPX))

Alternative Name: HOPX (HOPX Products)

Synonyms: CAMEO antibody, HOD antibody, HOP antibody, LAGY antibody, NECC1 antibody, OB1 antibody, SMAP31 antibody, TOTO antibody, 1110018K11Rik antibody, 1200015P04Rik antibody, 2300002F06Rik antibody, AI848177 antibody, AW490897 antibody, Cameo antibody, Hdop antibody, Hod antibody, Hop antibody, Ob1 antibody, Obl antibody, Toto antibody, GIIg15b antibody, HOPX antibody, hod antibody, hop antibody, ob1 antibody, lagy antibody, toto antibody, cameo antibody, necc1 antibody, smap31 antibody, MGC147344 antibody, HOP homeobox antibody, HOPX antibody, Hopx antibody, hopx antibody

Background:

Background: Atypical homeodomain protein which does not bind DNA and is required to modulate cardiac growth and development. Acts via its interaction with SRF, thereby modulating the expression of SRF-dependent cardiac-specific genes and cardiac development. Prevents SRF-dependent transcription either by inhibiting SRF binding to DNA or by recruiting histone deacetylase (HDAC) proteins that prevent transcription by SRF. Overexpression causes cardiac hypertrophy (By similarity). May act as a tumor suppressor.

Aliases: CAMEO antibody, heart odd homeobox 1 protein antibody, HOD antibody, Homeodomain-only protein antibody, HOP antibody, HOP homeobox antibody, HOP_HUMAN antibody, HOPX antibody, LAGY antibody, Lung cancer-associated Y protein antibody, NECC1 antibody, Not expressed in choriocarcinoma clone 1 antibody, Not expressed in choriocarcinoma protein 1 antibody, OB1 antibody, odd homeobox 1 protein antibody, Odd homeobox protein 1 antibody, OTTHUMP00000158970 antibody, SMAP31 antibody, TOTO antibody

UniProt: Q9BPY8

Pathways: Regulation of Muscle Cell Differentiation