HOPX antibody (AA 1-73)

Catalog No. ABIN7155873

Product Details anti-HOPX Antibody

Target: HOPX (HOP Homeobox (HOPX))

Binding Specificity: AA 1-73

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HOPX antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Homeodomain-only protein (1-73AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: IHC:1:20-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for HOPX

Target: HOPX (HOP Homeobox (HOPX))

Alternative Name: HOPX (HOPX Products)

Background:

Background: Atypical homeodomain protein which does not bind DNA and is required to modulate cardiac growth and development. Acts via its interaction with SRF, thereby modulating the expression of SRF-dependent cardiac-specific genes and cardiac development. Prevents SRF-dependent transcription either by inhibiting SRF binding to DNA or by recruiting histone deacetylase (HDAC) proteins that prevent transcription by SRF. Overexpression causes cardiac hypertrophy (By similarity). May act as a tumor suppressor.

Aliases: CAMEO antibody, heart odd homeobox 1 protein antibody, HOD antibody, Homeodomain-only protein antibody, HOP antibody, HOP homeobox antibody, HOP_HUMAN antibody, HOPX antibody, LAGY antibody, Lung cancer-associated Y protein antibody, NECC1 antibody, Not expressed in choriocarcinoma clone 1 antibody, Not expressed in choriocarcinoma protein 1 antibody, OB1 antibody, odd homeobox 1 protein antibody, Odd homeobox protein 1 antibody, OTTHUMP00000158970 antibody, SMAP31 antibody, TOTO antibody

UniProt: Q9BPY8

Pathways: Regulation of Muscle Cell Differentiation