TGIF1 antibody (AA 8-375)

Catalog No. ABIN7155852

Product Details anti-TGIF1 Antibody

Target: TGIF1 (TGFB-Induced Factor Homeobox 1 (TGIF1))

Binding Specificity: AA 8-375

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TGIF1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Cross-Reactivity: Human, Mouse

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Homeobox protein TGIF1 protein (8-375AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200, IF:1:50-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for TGIF1

Target: TGIF1 (TGFB-Induced Factor Homeobox 1 (TGIF1))

Alternative Name: TGIF1 (TGIF1 Products)

Background:

Background: Binds to a retinoid X receptor (RXR) responsive element from the cellular retinol-binding protein II promoter (CRBPII-RXRE). Inhibits the 9-cis-retinoic acid-dependent RXR alpha transcription activation of the retinoic acid responsive element. Active transcriptional corepressor of SMAD2. Links the nodal signaling pathway to the bifurcation of the forebrain and the establishment of ventral midline structures. May participate in the transmission of nuclear signals during development and in the adult, as illustrated by the down-modulation of the RXR alpha activities.

Aliases: 5' TG 3' interacting factor antibody, 5''-TG-3''-interacting factor 1 antibody, Homeobox protein TGIF antibody, Homeobox protein TGIF1 antibody, HPE4 antibody, MGC39747 antibody, MGC5066 antibody, TALE homeobox TG-interacting factor antibody, TG interacting factor isoform c antibody, TG-interacting factor antibody, TGFB induced factor antibody, TGFB-induced factor homeobox 1 antibody, TGIF1 antibody, TGIF1_HUMAN antibody, transforming growth factor-beta-induced factor antibody

UniProt: Q15583

Pathways: Retinoic Acid Receptor Signaling Pathway, Chromatin Binding, Tube Formation