HJURP antibody (AA 1-748) (Biotin)

Catalog No. ABIN7155634

Product Details anti-HJURP Antibody (Biotin)

Target: HJURP (Holliday Junction Recognition Protein (HJURP))

Binding Specificity: AA 1-748

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HJURP antibody is conjugated to Biotin

Application: ELISA

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Holliday junction recognition protein (1-748AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for HJURP

Target: HJURP (Holliday Junction Recognition Protein (HJURP))

Alternative Name: HJURP (HJURP Products)

Synonyms: Gm975 antibody, Mfleg1 antibody, MGC66590 antibody, C330011F01Rik antibody, FAKTS antibody, URLC9 antibody, hFLEG1 antibody, Holliday junction recognition protein antibody, Hjurp antibody, HJURP antibody

Background:

Background: Centromeric protein that plays a central role in the incorporation and maintenance of histone H3-like variant CENPA at centromeres. Acts as a specific chaperone for CENPA and is required for the incorporation of newly synthesized CENPA molecules into nucleosomes at replicated centromeres. Prevents CENPA-H4 tetramerization and prevents premature DNA binding by the CENPA-H4 tetramer. Directly binds Holliday junctions.

Aliases: HJURP antibody, FAKTS antibody, FLEG1 antibody, URLC9 antibody, Holliday junction recognition protein antibody, 14-3-3-associated AKT substrate antibody, Fetal liver-expressing gene 1 protein antibody, Up-regulated in lung cancer 9 antibody

UniProt: Q8NCD3