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SUV39H2 antibody (AA 201-410)

SUV39H2 Reactivity: Human WB, ELISA, IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7155529
  • Target See all SUV39H2 Antibodies
    SUV39H2 (Suppressor of Variegation 3-9 Homolog 2 (Drosophila) (SUV39H2))
    Binding Specificity
    • 13
    • 10
    • 8
    • 8
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 201-410
    Reactivity
    • 66
    • 29
    • 22
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 64
    • 2
    • 1
    Rabbit
    Clonality
    • 59
    • 8
    Polyclonal
    Conjugate
    • 33
    • 6
    • 4
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This SUV39H2 antibody is un-conjugated
    Application
    • 51
    • 37
    • 20
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    Cross-Reactivity
    Human
    Purification
    Antigen Affinity Purified
    Immunogen
    Recombinant Human Histone-lysine N-methyltransferase SUV39H2 protein (201-410AA)
    Isotype
    IgG
    Top Product
    Discover our top product SUV39H2 Primary Antibody
  • Application Notes
    Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200,
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C,-80 °C
    Storage Comment
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target
    SUV39H2 (Suppressor of Variegation 3-9 Homolog 2 (Drosophila) (SUV39H2))
    Alternative Name
    SUV39H2 (SUV39H2 Products)
    Synonyms
    KMT1B antibody, 4930507K23Rik antibody, AA536750 antibody, D030054H19Rik antibody, D2Ertd544e antibody, SUV39H2 antibody, kmt1b antibody, suppressor of variegation 3-9 homolog 2 antibody, suppressor of variegation 3-9 homolog 2 (Drosophila) antibody, suppressor of variegation 3-9 homolog 2 L homeolog antibody, SUV39H2 antibody, Suv39h2 antibody, suv39h2 antibody, suv39h2.L antibody
    Background

    Background: Histone methyltransferase that specifically trimethylates \\\'Lys-9\\\' of histone H3 using monomethylated H3 \\\'Lys-9\\\' as substrate. H3 \\\'Lys-9\\\' trimethylation represents a specific tag for epigenetic transcriptional repression by recruiting HP1 (CBX1, CBX3 and/or CBX5) proteins to methylated histones. Mainly functions in heterochromatin regions, thereby playing a central role in the establishment of constitutive heterochromatin at pericentric and telomere regions. H3 \\\'Lys-9\\\' trimethylation is also required to direct DNA methylation at pericentric repeats. SUV39H1 is targeted to histone H3 via its interaction with RB1 and is involved in many processes, such as cell cycle regulation, transcriptional repression and regulation of telomere length. May participate in regulation of higher-order chromatin organization during spermatogenesis. Recruited by the large PER complex to the E-box elements of the circadian target genes such as PER2 itself or PER1, contributes to the conversion of local chromatin to a heterochromatin-like repressive state through H3 \\\'Lys-9\\\' trimethylation.

    Aliases: FLJ23414 antibody, H3 K9 HMTase 2 antibody, H3-K9-HMTase 2 antibody, Histone H3 K9 methyltransferase 2 antibody, Histone H3-K9 methyltransferase 2 antibody, Histone lysine N methyltransferase H3 lysine 9 specific 2 antibody, Histone lysine N methyltransferase SUV39H2 antibody, Histone-lysine N-methyltransferase SUV39H2 antibody, KMT1B antibody, Lysine N methyltransferase 1B antibody, Lysine N-methyltransferase 1B antibody, sSuppressor of variegation 3 9 homolog 2 (Drosophila) antibody, Su(var)3 9 Drosophila homolog of 2 antibody, Su(var)3 9 homolog 2 antibody, Su(var)3-9 homolog 2 antibody, Suppressor of variegation 3 9 homolog 2 antibody, Suppressor of variegation 3-9 homolog 2 antibody, Suv39h2 antibody, SUV92_HUMAN antibody

    UniProt
    Q9H5I1
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