H2AFB1 antibody (AA 1-115)
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- Target See all H2AFB1 Antibodies
- H2AFB1 (H2A Histone Family, Member B1 (H2AFB1))
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Binding Specificity
- AA 1-115
- Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This H2AFB1 antibody is un-conjugated
- Application
- ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
- Cross-Reactivity
- Human
- Purification
- >95%, Protein G purified
- Immunogen
- Recombinant Human Histone H2A-Bbd type 1 protein (1-115AA)
- Isotype
- IgG
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anti-H2A Histone Family, Member B1 (H2AFB1) (N-Term) antibody
H2AFB1 Reactivity: Human WB Host: Rabbit Polyclonal unconjugated
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- Application Notes
- Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200,
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 - Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Target
- H2AFB1 (H2A Histone Family, Member B1 (H2AFB1))
- Alternative Name
- H2AFB1 (H2AFB1 Products)
- Synonyms
- H2A.Bbd antibody, H2A histone family member B1 antibody, H2AFB1 antibody
- Background
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Background: Atypical histone H2A which can replace conventional H2A in some nucleosomes and is associated with active transcription and mRNA processing. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. Nucleosomes containing this histone are less rigid and organize less DNA than canonical nucleosomes in vivo. They are enriched in actively transcribed genes and associate with the elongating form of RNA polymerase. They associate with spliceosome components and are required for mRNA splicing. May participate in spermatogenesis.
Aliases: H2AB1 antibody, H2AFB1 antibody, Histone H2A-Bbd type 1 antibody, H2A Barr body-deficient antibody, H2A.B antibody, H2A.Bbd antibody
- UniProt
- P0C5Y9
- Pathways
- Telomere Maintenance
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