HAT1 antibody (Catalytic Subunit) (Biotin)

Catalog No. ABIN7155292

Product Details anti-HAT1 Antibody (Biotin)

Target: HAT1 (Histone Acetyltransferase 1 (HAT1))

Binding Specificity: AA 245-419, Catalytic Subunit

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HAT1 antibody is conjugated to Biotin

Application: ELISA

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Histone acetyltransferase type B catalytic subunit protein (245-419AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for HAT1

Target: HAT1 (Histone Acetyltransferase 1 (HAT1))

Alternative Name: HAT1 (HAT1 Products)

Synonyms: KAT1 antibody, HAC07 antibody, HAC7 antibody, HAG02 antibody, MIK19.19 antibody, MIK19_19 antibody, histone acetyltransferase of the GNAT family 2 antibody, hac106 antibody, hat1 antibody, zgc:92639 antibody, histone acetyltransferase 1 antibody, histone acetyltransferase of the GNAT family 2 antibody, histone acetyltransferase catalytic subunit antibody, histone acetyltransferase Hat1 antibody, histone acetyltransferase 1 L homeolog antibody, HAT1 antibody, Hat1 antibody, HAG2 antibody, hat1 antibody, hat1.L antibody

Background:

Background: Acetylates soluble but not nucleosomal histone H4 at \'Lys-5\' (H4K5ac) and \'Lys-12\' (H4K12ac) and, to a lesser extent, acetylates histone H2A at \'Lys-5\' (H2AK5ac). Has intrinsic substrate specificity that modifies lysine in recognition sequence GXGKXG. May be involved in nucleosome assembly during DNA replication and repair as part of the histone H3.1 and H3.3 complexes. May play a role in DNA repair in response to free radical damage.

Aliases: HAT 1 antibody, hat1 antibody, HAT1_HUMAN antibody, Histidine aminotransferase 1 antibody, Histone acetyltransferase 1 antibody, Histone acetyltransferase 1 antibody, Histone acetyltransferase type B catalytic subunit antibody, KAT1 antibody

UniProt: O14929