KAT5 antibody (AA 3-512)

Catalog No. ABIN7155274

Product Details anti-KAT5 Antibody

Target: KAT5 (K(lysine) Acetyltransferase 5 (KAT5))

Binding Specificity: AA 3-512

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KAT5 antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Histone acetyltransferase KAT5 protein (3-512AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: WB:1:500-1:5000, IHC:1:500-1:1000, IF:1:50-1:500,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for KAT5

Target: KAT5 (K(lysine) Acetyltransferase 5 (KAT5))

Alternative Name: KAT5 (KAT5 Products)

Synonyms: 6121 antibody, CG6121 antibody, DmEG0007.7 antibody, Dmel/TIP60 antibody, Dmel\\CG6121 antibody, Dmel\\TIP60 antibody, EG0007.7 antibody, EG:EG0007.7 antibody, TIP60 antibody, dTIP60 antibody, dTip60 antibody, dmHAG405 antibody, im:6908768 antibody, wu:fb55b08 antibody, zgc:110752 antibody, ESA1 antibody, HTATIP antibody, HTATIP1 antibody, PLIP antibody, TIP antibody, ZC2HC5 antibody, cPLA2 antibody, AI839539 antibody, CPLA2 antibody, Htatip antibody, Htatip1 antibody, Tip55 antibody, Tip60 antibody, K(lysine) acetyltransferase 5a antibody, lysine acetyltransferase 5 antibody, Tat interactive protein 60kDa antibody, histone acetyltransferase Tip60 antibody, tip60, putative antibody, K(lysine) acetyltransferase 5b antibody, K(lysine) acetyltransferase 5 antibody, kat5a antibody, KAT5 antibody, Tip60 antibody, LOC413101 antibody, LOC5579231 antibody, Smp_053140 antibody, kat5b antibody, Kat5 antibody

Background:

Background: Catalytic subunit of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A. This modification may both alter nucleosome-DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis, and DNA repair. NuA4 may also play a direct role in DNA repair when recruited to sites of DNA damage. Directly acetylates and activates ATM. In case of HIV-1 infection, interaction with the viral Tat protein leads to KAT5 polyubiquitination and targets it to degradation.

Aliases: 60 kDa Tat interactive protein antibody, 60 kDa Tat-interactive protein antibody, cPLA(2) interacting protein antibody, cPLA(2)-interacting protein antibody, cPLA2 antibody, cPLA2 interacting protein antibody, ESA1 antibody, Histone acetyltransferase HTATIP antibody, Histone acetyltransferase KAT5 antibody, HIV 1 Tat interactive protein antibody, HIV 1 Tat interactive protein, 60 kDa antibody, HIV-1 Tat interactive protein antibody, HTATIP antibody, HTATIP1 antibody, K(lysine) acetyltransferase 5 antibody, K-acetyltransferase 5 antibody, KAT5 antibody, KAT5_HUMAN antibody, Lysine acetyltransferase 5 antibody, PLIP antibody, Tat interacting protein, 60 kDa antibody, TIP antibody, Tip60 antibody

UniProt: Q92993

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway