HMGN3 antibody (AA 1-77)

Catalog No. ABIN7155196

Product Details anti-HMGN3 Antibody

Target: HMGN3 (High Mobility Group Nucleosomal Binding Domain 3 (HMGN3))

Binding Specificity: AA 1-77

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HMGN3 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human High mobility group nucleosome-binding domain-containing protein 3 protein (1-77AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: IHC:1:20-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for HMGN3

Target: HMGN3 (High Mobility Group Nucleosomal Binding Domain 3 (HMGN3))

Alternative Name: HMGN3 (HMGN3 Products)

Synonyms: Trip7 antibody, PNAS-25 antibody, TRIP7 antibody, 1110002A15Rik antibody, 6330514M13Rik antibody, BB071015 antibody, high mobility group nucleosomal binding domain 3 L homeolog antibody, high mobility group nucleosomal binding domain 3 antibody, hmgn3.L antibody, HMGN3 antibody, Hmgn3 antibody

Background:

Background: Binds to nucleosomes, regulating chromatin structure and consequently, chromatin-dependent processes such as transcription, DNA replication and DNA repair. Affects both insulin and glucagon levels and modulates the expression of pancreatic genes involved in insulin secretion. Regulates the expression of the glucose transporter SLC2A2 by binding specifically to its promoter region and recruiting PDX1 and additional transcription factors. Regulates the expression of SLC6A9, a glycine transporter which regulates the glycine concentration in synaptic junctions in the central nervous system, by binding to its transcription start site. May play a role in ocular development and astrocyte function (By similarity).

Aliases: DKFZp686E20226 antibody, FLJ42187 antibody, High mobility group nucleosomal binding domain 3 antibody, High mobility group nucleosome-binding domain-containing protein 3 antibody, HMGN3 antibody, HMGN3_HUMAN antibody, OTTHUMP00000016772 antibody, OTTHUMP00000016773 antibody, PNAS 24 antibody, PNAS 25 antibody, PNAS24 antibody, PNAS25 antibody, Thyroid hormone receptor interacting protein 7 antibody, Thyroid receptor-interacting protein 7 antibody, TR-interacting protein 7 antibody, TRIP 7 antibody, TRIP-7 antibody, TRIP7 antibody

UniProt: Q15651