HPS6 antibody (AA 221-319)

Catalog No. ABIN7155077

Product Details anti-HPS6 Antibody

Target: HPS6 (Hermansky-Pudlak Syndrome 6 (HPS6))

Binding Specificity: AA 221-319

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HPS6 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Hermansky-Pudlak syndrome 6 protein (221-319AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: IHC:1:200-1:500, IF:1:50-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for HPS6

Target: HPS6 (Hermansky-Pudlak Syndrome 6 (HPS6))

Alternative Name: HPS6 (HPS6 Products)

Synonyms: RP11-302K17.1 antibody, 5330434M19Rik antibody, BLOC2 antibody, ru antibody, Hsp6 antibody, HPS6, biogenesis of lysosomal organelles complex 2 subunit 3 antibody, HPS6 antibody, hps6 antibody, Hps6 antibody

Background:

Background: May regulate the synthesis and function of lysosomes and of highly specialized organelles, such as melanosomes and platelet dense granules (PubMed:17041891). Acts as cargo adapter for the dynein-dynactin motor complex to mediate the transport of lysosomes from the cell periphery to the perinuclear region. Facilitates retrograde lysosomal trafficking by linking the motor complex to lysosomes, and perinuclear positioning of lysosomes is crucial for the delivery of endocytic cargos to lysosomes, for lysosome maturation and functioning (PubMed:25189619).

Aliases: BLOC2S3 antibody, FLJ22501 antibody, Hermansky Pudlak syndrome 6 protein antibody, Hermansky-Pudlak syndrome 6 protein antibody, HPS6 antibody, HPS6 biogenesis of lysosomal organelles complex 2 subunit 3 antibody, HPS6_HUMAN antibody, MGC20522 antibody, Ru antibody, Ruby eye protein homolog antibody, Ruby-eye protein homolog antibody

UniProt: Q86YV9