TRAP1 antibody (AA 60-308)
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- Target See all TRAP1 Antibodies
- TRAP1 (TNF Receptor-Associated Protein 1 (TRAP1))
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Binding Specificity
- AA 60-308
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This TRAP1 antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunoprecipitation (IP)
- Cross-Reactivity
- Human, Mouse
- Purification
- >95%, Protein G purified
- Immunogen
- Recombinant Human Heat shock protein 75 kDa, mitochondrial protein (60-308AA)
- Isotype
- IgG
- Top Product
- Discover our top product TRAP1 Primary Antibody
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- Application Notes
- Recommended dilution: WB:1:1000-1:5000, IF:1:50-1:200, IP:1:200-1:2000,
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 - Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Target
- TRAP1 (TNF Receptor-Associated Protein 1 (TRAP1))
- Alternative Name
- TRAP1 (TRAP1 Products)
- Synonyms
- HSP 75 antibody, HSP75 antibody, HSP90L antibody, TRAP-1 antibody, 2410002K23Rik antibody, fc85a11 antibody, wu:fc85a11 antibody, TNF receptor associated protein 1 antibody, TNF receptor-associated protein 1 antibody, TRAP1 antibody, Trap1 antibody, trap1 antibody
- Background
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Background: Chaperone that expresses an ATPase activity. Involved in maintaining mitochondrial function and polarization, downstream of PINK1 and mitochondrial complex I. Is a negative regulator of mitochondrial respiration able to modulate the balance between oxidative phosphorylation and aerobic glycolysis. The impact of TRAP1 on mitochondrial respiration is probably mediated by modulation of mitochondrial SRC and inhibition of SDHA.
Aliases: Heat shock protein 75 kDa antibody, Heat shock protein 75 kDa, mitochondrial antibody, HSP 75 antibody, HSP75 antibody, HSP90L antibody, mitochondrial antibody, TNF receptor associated protein 1 antibody, TNFR-associated protein 1 antibody, TRAP-1 antibody, Trap1 antibody, TRAP1_HUMAN antibody, Tumor necrosis factor type 1 receptor-associated protein antibody
- UniProt
- Q12931
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