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Hsc70 antibody (AA 2-646)

HSPA8 Reactivity: Human WB, IHC, ELISA, IP, FACS Host: Mouse Monoclonal 2G8F6 unconjugated
Catalog No. ABIN7154883
  • Target See all Hsc70 (HSPA8) Antibodies
    Hsc70 (HSPA8) (Heat Shock 70kDa Protein 8 (HSPA8))
    Binding Specificity
    • 14
    • 7
    • 6
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 2-646
    Reactivity
    • 81
    • 48
    • 44
    • 21
    • 17
    • 14
    • 13
    • 11
    • 11
    • 11
    • 10
    • 10
    • 5
    • 5
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 70
    • 27
    • 7
    • 2
    Mouse
    Clonality
    • 70
    • 35
    Monoclonal
    Conjugate
    • 58
    • 19
    • 11
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Hsc70 antibody is un-conjugated
    Application
    • 92
    • 51
    • 39
    • 29
    • 28
    • 28
    • 15
    • 13
    • 11
    • 11
    • 11
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunoprecipitation (IP), Flow Cytometry (FACS)
    Cross-Reactivity
    Human, Mouse, Rat
    Purification
    Protein A purified
    Immunogen
    Recombinant Human Heat shock cognate 71 kDa protein (2-646AA)
    Clone
    2G8F6
    Isotype
    IgG2b
    Top Product
    Discover our top product HSPA8 Primary Antibody
  • Application Notes
    Recommended dilution: WB: 1:10000-1:256000, IHC: 1:100-1:500, FC: 1:100-1:300, IP: 1 μL-4 μL,
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C,-80 °C
    Storage Comment
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target
    Hsc70 (HSPA8) (Heat Shock 70kDa Protein 8 (HSPA8))
    Alternative Name
    HSPA8 (HSPA8 Products)
    Synonyms
    hsc54 antibody, hsc70 antibody, hsc71 antibody, hsp71 antibody, hsp73 antibody, hspa10 antibody, lap1 antibody, nip71 antibody, HSC54 antibody, HSC70 antibody, HSC71 antibody, HSP71 antibody, HSP73 antibody, HSPA10 antibody, LAP1 antibody, NIP71 antibody, Hsc70 antibody, 2410008N15Rik antibody, Hsc71 antibody, Hsc73 antibody, Hsp73 antibody, Hspa10 antibody, wu:fb01g06 antibody, wu:fi48b06 antibody, heat shock protein family A (Hsp70) member 8 L homeolog antibody, heat shock protein family A (Hsp70) member 8 antibody, heat shock 70kDa protein 8 antibody, heat shock protein 8 antibody, hspa8.L antibody, HSPA8 antibody, Hspa8 antibody, hspa8 antibody
    Background

    Background: Acts as a repressor of transcriptional activation. Inhibits the transcriptional coactivator activity of CITED1 on Smad-mediated transcription. Chaperone. Component of the PRP19-CDC5L complex that forms an integral part of the spliceosome and is required for activating pre-mRNA splicing. May have a scaffolding role in the spliceosome assembly as it contacts all other components of the core complex. Binds bacterial lipopolysaccharide (LPS) et mediates LPS-induced inflammatory response, including TNF secretion by monocytes. Participates in the ER-associated degradation (ERAD) quality control pathway in conjunction with J domain-containing co-chaperones and the E3 ligase CHIP

    Aliases: Heat shock cognate 71 kDa protein (Heat shock 70 kDa protein 8) (Lipopolysaccharide-associated protein 1) (LAP-1) (LPS-associated protein 1), HSPA8, HSC70 HSP73 HSPA10

    UniProt
    P11142
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