Hsc70 antibody (AA 2-646)
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- Target See all Hsc70 (HSPA8) Antibodies
- Hsc70 (HSPA8) (Heat Shock 70kDa Protein 8 (HSPA8))
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Binding Specificity
- AA 2-646
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This Hsc70 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunoprecipitation (IP), Flow Cytometry (FACS)
- Cross-Reactivity
- Human, Mouse, Rat
- Purification
- Protein A purified
- Immunogen
- Recombinant Human Heat shock cognate 71 kDa protein (2-646AA)
- Clone
- 2G8F6
- Isotype
- IgG2b
- Top Product
- Discover our top product HSPA8 Primary Antibody
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anti-Heat Shock 70kDa Protein 8 (HSPA8) (AA 2-646) antibody
HSPA8 Reactivity: Human WB, IHC, ELISA, IF, FACS Host: Mouse Monoclonal 6E4D2 unconjugated
anti-Heat Shock 70kDa Protein 8 (HSPA8) (C-Term) antibodyHSPA8 Reactivity: Human, Rat, Mouse WB, ICC, IF, IHC (p) Host: Rabbit Polyclonal unconjugated
anti-Heat Shock 70kDa Protein 8 (HSPA8) (AA 1-300) antibodyHSPA8 Reactivity: Human WB, IHC, IF Host: Rabbit Polyclonal unconjugated
anti-Heat Shock 70kDa Protein 8 (HSPA8) (AA 82-110), (N-Term) antibodyHSPA8 Reactivity: Human WB, IF, IHC (p), FACS Host: Rabbit Polyclonal RB17655 unconjugated
anti-Heat Shock 70kDa Protein 8 (HSPA8) (AA 539-569), (C-Term) antibodyHSPA8 Reactivity: Human WB, IF, IHC (p), FACS Host: Rabbit Polyclonal RB16528 unconjugated
anti-Heat Shock 70kDa Protein 8 (HSPA8) antibodyHSPA8 Reactivity: Human WB, IHC, ELISA, IP, ICC, IF, Bind, PLA, AA Host: Mouse Monoclonal 1F2-H5 unconjugated
anti-Heat Shock 70kDa Protein 8 (HSPA8) (AA 13-31), (N-Term) antibodyHSPA8 Reactivity: Human, Rat, Mouse WB, ICC, IHC (p), IHC (fro) Host: Rabbit Polyclonal unconjugated
anti-Heat Shock 70kDa Protein 8 (HSPA8) (N-Term) antibodyHSPA8 Reactivity: Human, Rat, Mouse, Cow, Sheep, Pig, Zebrafish (Danio rerio), Goat WB, IHC Host: Rabbit Polyclonal unconjugated
anti-Heat Shock 70kDa Protein 8 (HSPA8) (AA 534-615) antibodyHSPA8 Reactivity: Mouse WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated
anti-Heat Shock 70kDa Protein 8 (HSPA8) (AA 418-597) antibodyHSPA8 Reactivity: Human WB, IHC, ELISA Host: Rabbit Polyclonal unconjugated
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- Application Notes
- Recommended dilution: WB: 1:10000-1:256000, IHC: 1:100-1:500, FC: 1:100-1:300, IP: 1 μL-4 μL,
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 - Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Target
- Hsc70 (HSPA8) (Heat Shock 70kDa Protein 8 (HSPA8))
- Alternative Name
- HSPA8 (HSPA8 Products)
- Background
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Background: Acts as a repressor of transcriptional activation. Inhibits the transcriptional coactivator activity of CITED1 on Smad-mediated transcription. Chaperone. Component of the PRP19-CDC5L complex that forms an integral part of the spliceosome and is required for activating pre-mRNA splicing. May have a scaffolding role in the spliceosome assembly as it contacts all other components of the core complex. Binds bacterial lipopolysaccharide (LPS) et mediates LPS-induced inflammatory response, including TNF secretion by monocytes. Participates in the ER-associated degradation (ERAD) quality control pathway in conjunction with J domain-containing co-chaperones and the E3 ligase CHIP
Aliases: Heat shock cognate 71 kDa protein (Heat shock 70 kDa protein 8) (Lipopolysaccharide-associated protein 1) (LAP-1) (LPS-associated protein 1), HSPA8, HSC70 HSP73 HSPA10
- UniProt
- P11142
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