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TSC1 antibody (AA 101-344)

TSC1 Reactivity: Human ELISA, IHC, IF Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7154826
  • Target See all TSC1 Antibodies
    TSC1 (Tuberous Sclerosis 1 (TSC1))
    Binding Specificity
    • 24
    • 16
    • 16
    • 16
    • 15
    • 15
    • 13
    • 8
    • 8
    • 8
    • 8
    • 8
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 6
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 101-344
    Reactivity
    • 187
    • 139
    • 53
    • 24
    • 18
    • 2
    • 1
    • 1
    Human
    Host
    • 301
    • 16
    • 1
    • 1
    Rabbit
    Clonality
    • 303
    • 16
    Polyclonal
    Conjugate
    • 113
    • 37
    • 36
    • 36
    • 32
    • 32
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    This TSC1 antibody is un-conjugated
    Application
    • 229
    • 208
    • 92
    • 27
    • 26
    • 26
    • 15
    • 14
    • 9
    • 7
    • 6
    • 4
    • 3
    • 1
    ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
    Cross-Reactivity
    Human
    Purification
    >95%, Protein G purified
    Immunogen
    Recombinant Human Hamartin protein (101-344AA)
    Isotype
    IgG
    Top Product
    Discover our top product TSC1 Primary Antibody
  • Application Notes
    Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200,
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C,-80 °C
    Storage Comment
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target
    TSC1 (Tuberous Sclerosis 1 (TSC1))
    Alternative Name
    TSC1 (TSC1 Products)
    Synonyms
    LAM antibody, TSC antibody, hamartin antibody, mKIAA0243 antibody, tsc1 antibody, wu:fc38b04 antibody, fa99f04 antibody, wu:fa99f04 antibody, zgc:63657 antibody, TSC complex subunit 1 antibody, tuberous sclerosis 1 antibody, TSC complex subunit 1b antibody, TSC complex subunit 1a antibody, TSC1 antibody, Tsc1 antibody, tsc1b antibody, tsc1 antibody, tsc1a antibody
    Background

    Background: In complex with TSC2, inhibits the nutrient-mediated or growth factor-stimulated phosphorylation of S6K1 and EIF4EBP1 by negatively regulating mTORC1 signaling. Seems not to be required for TSC2 GAP activity towards RHEB. Implicated as a tumor suppressor. Involved in microtubule-mediated protein transport, but this seems to be due to unregulated mTOR signaling.

    Aliases: Hamartin antibody, kiaa0243 antibody, LAM antibody, TSC antibody, Tsc1 antibody, Tsc1 gene antibody, TSC1_HUMAN antibody, Tuberous sclerosis 1 antibody, Tuberous sclerosis 1 protein antibody, tumor suppressor antibody

    UniProt
    Q92574
    Pathways
    RTK Signaling, AMPK Signaling, Regulation of Cell Size, Tube Formation
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