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HEY1 antibody (AA 200-300) (Biotin)

HEY1 Reactivity: Human ELISA Host: Rabbit Polyclonal Biotin
Catalog No. ABIN7154815
  • Target See all HEY1 Antibodies
    HEY1 (Ha-Ry/enhancer-of-Split Related with YRPW Motif 1 (HEY1))
    Binding Specificity
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 200-300
    Reactivity
    • 27
    • 10
    • 9
    • 6
    • 5
    • 5
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 19
    • 7
    • 1
    Rabbit
    Clonality
    • 21
    • 6
    Polyclonal
    Conjugate
    • 24
    • 2
    • 1
    This HEY1 antibody is conjugated to Biotin
    Application
    • 22
    • 12
    • 6
    • 6
    • 2
    • 1
    • 1
    • 1
    ELISA
    Cross-Reactivity
    Human
    Purification
    >95%, Protein G purified
    Immunogen
    Recombinant Human Hairy/enhancer-of-split related with YRPW motif protein 1 protein (200-300AA)
    Isotype
    IgG
    Top Product
    Discover our top product HEY1 Primary Antibody
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C,-80 °C
    Storage Comment
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target
    HEY1 (Ha-Ry/enhancer-of-Split Related with YRPW Motif 1 (HEY1))
    Alternative Name
    HEY1 (HEY1 Products)
    Synonyms
    BHLHb31 antibody, CHF2 antibody, HERP2 antibody, HESR1 antibody, HRT-1 antibody, OAF1 antibody, AI316788 antibody, AI414254 antibody, HRT1 antibody, Herp2 antibody, Hesr1 antibody, bHLHb31 antibody, hesr-1 antibody, id:ibd1292 antibody, zgc:110572 antibody, bc8 antibody, chf2 antibody, herp2 antibody, hesr1 antibody, hrt1 antibody, oaf1 antibody, xbc8 antibody, hes related family bHLH transcription factor with YRPW motif 1 antibody, hairy/enhancer-of-split related with YRPW motif 1 antibody, hes-related family bHLH transcription factor with YRPW motif 1 antibody, hes related family bHLH transcription factor with YRPW motif 1 S homeolog antibody, HEY1 antibody, Hey1 antibody, hey1 antibody, hey1.S antibody
    Background

    Background: Transcriptional repressor which binds preferentially to the canonical E box sequence 5\'-CACGTG-3\' (PubMed:11095750). Downstream effector of Notch signaling required for cardiovascular development. Specifically required for the Notch-induced endocardial epithelial to mesenchymal transition, which is itself criticial for cardiac valve and septum development. May be required in conjunction with HEY2 to specify arterial cell fate or identity. Promotes maintenance of neuronal precursor cells and glial versus neuronal fate specification. Represses transcription by the cardiac transcriptional activators GATA4 and GATA6 and by the neuronal bHLH factors ASCL1/MASH1 and NEUROD4/MATH3 (PubMed:15485867). Involved in the regulation of liver cancer cells self-renewal (PubMed:25985737).

    Aliases: Basic helix loop helix protein OAF1 antibody, bHLHb31 antibody, Cardiovascular helix loop-helix factor 2 antibody, Cardiovascular helix-loop-helix factor 2 antibody, CHF-2 antibody, CHF2 antibody, Class B basic helix-loop-helix protein 31 antibody, Hairy and enhancer of split related protein 1 antibody, Hairy and enhancer of split-related protein 1 antibody, Hairy enhancer-of-split related with YRPW motif protein 1 antibody, Hairy related transcription factor 1 antibody, Hairy-related transcription factor 1 antibody, Hairy/enhancer of split related with YRPW motif 1 antibody, Hairy/enhancer-of-split related with YRPW motif protein 1 antibody, HERP2 antibody, HES related repressor protein 1 antibody, HES-related repressor protein 1 antibody, HES-related repressor protein 2 antibody, HESR-1 antibody, HESR1 antibody, HEY 1 antibody, hey1 antibody, HEY1_HUMAN antibody, hHRT1 antibody, HRT-1 antibody, HRT1 antibody, OAF1 antibody

    UniProt
    Q9Y5J3
    Pathways
    Tube Formation
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