GBP5 antibody (AA 321-500)

Catalog No. ABIN7154781

Product Details anti-GBP5 Antibody

Target: GBP5 (Guanylate Binding Protein 5 (GBP5))

Binding Specificity: AA 321-500

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GBP5 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Cross-Reactivity: Human, Mouse

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Guanylate-binding protein 5 protein (321-500AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: WB:1:500-1:2000, IHC:1:20-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for GBP5

Target: GBP5 (Guanylate Binding Protein 5 (GBP5))

Alternative Name: GBP5 (GBP5 Products)

Synonyms: GBP-5 antibody, 5330409J06Rik antibody, Gbp5a antibody, guanylate binding protein 5 antibody, guanylate-binding protein 5 antibody, GBP5 antibody, gbp5 antibody, LOC100469548 antibody, Gbp5 antibody

Background:

Background: As an activator of NLRP3 inflammasome assembly, plays a role in innate immunity and inflammation. Promotes selective NLRP3 inflammasome assembly in response to microbial and soluble, but not crystalline, agents (PubMed:22461501). Hydrolyzes GTP, but in contrast to other family members, does not produce GMP (PubMed:20180847).

Aliases: GBP 5 antibody, GBP TA antigen antibody, GBP-5 antibody, GBP-TA antigen antibody, GBP5 antibody, GBP5_HUMAN antibody, GTP binding protein 5 antibody, GTP-binding protein 5 antibody, Guanine nucleotide binding protein 5 antibody, Guanine nucleotide-binding protein 5 antibody, Guanylate binding protein 5 antibody, Guanylate-binding protein 5 antibody, UNQ2427/PRO4987 antibody

UniProt: Q96PP8