GNL3L antibody (AA 1-582)
-
- Target See all GNL3L Antibodies
- GNL3L (Guanine Nucleotide Binding Protein-Like 3 (Nucleolar)-Like (GNL3L))
-
Binding Specificity
- AA 1-582
-
Reactivity
- Human
-
Host
- Rabbit
-
Clonality
- Polyclonal
-
Conjugate
- This GNL3L antibody is un-conjugated
-
Application
- ELISA
- Cross-Reactivity
- Human
- Purification
- >95%, Protein G purified
- Immunogen
- Recombinant Human Guanine nucleotide-binding protein-like 3-like protein (1-582AA)
- Isotype
- IgG
- Top Product
- Discover our top product GNL3L Primary Antibody
-
-
- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Buffer
-
Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 - Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
-
- Target
- GNL3L (Guanine Nucleotide Binding Protein-Like 3 (Nucleolar)-Like (GNL3L))
- Alternative Name
- GNL3L (GNL3L Products)
- Synonyms
- SI:zK13A21.8 antibody, flj10613 antibody, flj10613l antibody, si:dkey-13a21.8 antibody, zgc:110536 antibody, BC020354 antibody, guanine nucleotide binding protein-like 3 (nucleolar)-like antibody, guanine nucleotide binding protein-like 3 (nucleolar)-like S homeolog antibody, G protein nucleolar 3 like antibody, gnl3l antibody, gnl3l.S antibody, GNL3L antibody, Gnl3l antibody
- Background
-
Background: Stabilizes TERF1 telomeric association by preventing TERF1 recruitment by PML. Stabilizes TERF1 protein by preventing its ubiquitination and hence proteasomal degradation. Does so by interfering with TERF1-binding to FBXO4 E3 ubiquitin-protein ligase. Required for cell proliferation. By stabilizing TRF1 protein during mitosis, promotes metaphase-to-anaphase transition. Stabilizes MDM2 protein by preventing its ubiquitination, and hence proteasomal degradation. By acting on MDM2, may affect TP53 activity. Required for normal processing of ribosomal pre-rRNA. Binds GTP.
Aliases: GNL3LGuanine nucleotide-binding protein-like 3-like protein antibody
- UniProt
- Q9NVN8
-