GNAS antibody (AA 1-394)
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- Target See all GNAS Antibodies
- GNAS (GNAS Complex Locus (GNAS))
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Binding Specificity
- AA 1-394
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This GNAS antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
- Cross-Reactivity
- Human, Mouse, Rat
- Purification
- >95%, Protein G purified
- Immunogen
- Recombinant Human Guanine nucleotide-binding protein G(s) subunit alpha isoforms short protein (1-394AA)
- Isotype
- IgG
- Top Product
- Discover our top product GNAS Primary Antibody
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- Application Notes
- Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200, IF:1:50-1:200,
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 - Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Target
- GNAS (GNAS Complex Locus (GNAS))
- Alternative Name
- GNAS (GNAS Products)
- Synonyms
- AHO antibody, C20orf45 antibody, GNAS1 antibody, GPSA antibody, GSA antibody, GSP antibody, NESP antibody, PHP1A antibody, PHP1B antibody, PHP1C antibody, POH antibody, GNAS antibody, PORGSA1 antibody, G-alpha-S antibody, 5530400H20Rik antibody, A930027G11Rik antibody, C130027O20Rik antibody, Galphas antibody, Gnas1 antibody, Gnasxl antibody, Gsa antibody, Nesp antibody, Nespl antibody, Oed-Sml antibody, Oedsml antibody, P1 antibody, P2 antibody, P3 antibody, G-alpha-s antibody, gnas-a antibody, Gnpas antibody, Nesp55 antibody, gnal antibody, Gnas antibody, GNAS complex locus antibody, guanine nucleotide-binding protein G(s) subunit alpha antibody, GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus antibody, GNAS complex locus S homeolog antibody, neuroendocrine secretory protein 55-like antibody, GNAS antibody, LOC694289 antibody, LOC469986 antibody, Gnas antibody, gnas.S antibody, gnas antibody, LOC100346323 antibody, LOC100442753 antibody, LOC100732436 antibody
- Background
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Background: Guanine nucleotide-binding proteins (G proteins) function as transducers in numerous signaling pathways controlled by G protein-coupled receptors (GPCRs) (PubMed:17110384). Signaling involves the activation of adenylyl cyclases, resulting in increased levels of the signaling molecule cAMP (PubMed:26206488, PubMed:8702665). GNAS functions downstream of several GPCRs, including beta-adrenergic receptors (PubMed:21488135). Stimulates the Ras signaling pathway via RAPGEF2 (PubMed:12391161).
Aliases: Adenylate cyclase-stimulating G alpha protein antibody, AHO antibody, alternative gene product encoded by XL-exon antibody, C20orf45 antibody, extra large alphas protein antibody, GNAS antibody, GNAS complex locus antibody, GNAS1 antibody, GNAS1 gene, formerly antibody, GNAS1, formerly antibody, GNAS2_HUMAN antibody, GPSA antibody, GSA antibody, GSP antibody, guanine nucleotide binding protein (G protein), alpha stimulating activity polypeptide 1 antibody, guanine nucleotide regulatory protein antibody, Guanine nucleotide-binding protein G(s) subunit alpha isoforms short antibody, guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas antibody, NESP antibody, neuroendocrine secretory protein antibody, PHP1A antibody, PHP1B antibody, PHP1C antibody, POH antibody, protein ALEX antibody, secretogranin VI antibody
- UniProt
- P63092
- Pathways
- Thyroid Hormone Synthesis, cAMP Metabolic Process, Myometrial Relaxation and Contraction, Embryonic Body Morphogenesis
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