GDF5 antibody (AA 202-501)

Catalog No. ABIN7154549

Product Details anti-GDF5 Antibody

Target: GDF5 (Growth Differentiation Factor 5 (GDF5))

Binding Specificity: AA 202-501

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GDF5 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Cross-Reactivity: Human

Purification: Antigen Affinity Purified

Immunogen: Recombinant Human Growth/differentiation factor 5 protein (202-501AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200, IF:1:20-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for GDF5

Target: GDF5 (Growth Differentiation Factor 5 (GDF5))

Alternative Name: GDF5 (GDF5 Products)

Synonyms: CDMP1 antibody, gdf antibody, gdf-5 antibody, GDF5 antibody, BDA1C antibody, BMP14 antibody, LAP4 antibody, OS5 antibody, SYM1B antibody, SYNS2 antibody, Cdmp-1 antibody, bp antibody, brp antibody, Cdmp1 antibody, growth differentiation factor 5 L homeolog antibody, growth differentiation factor 5 antibody, gdf5.L antibody, GDF5 antibody, Gdf5 antibody

Background:

Background: Required to prevent excessive muscle loss upon denervation. This function requires SMAD4 and is mediated by phosphorylated SMAD1/5/8 (By similarity). Could be involved in bone and cartilage formation. Chondrogenic signaling is mediated by the high-affinity receptor BMPR1B. Binds bacterial lipopolysaccharide (LPS) et mediates LPS-induced inflammatory response, including TNF secretion by monocytes.

Aliases: BMP14 antibody, Cartilage derived morphogenetic protein 1 antibody, Cartilage-derived morphogenetic protein 1 antibody, CDMP-1 antibody, CDMP1 antibody, GDF-5 antibody, Gdf5 antibody, GDF5_HUMAN antibody, Growth differentiation factor 5 antibody, Growth/differentiation factor 5 antibody, LAP4 antibody, OS5 antibody, Radotermin antibody, SYNS2 antibody

UniProt: P43026