GGT1 antibody (AA 13-225)

Catalog No. ABIN7154060

Product Details anti-GGT1 Antibody

Target: GGT1 (gamma Glutamyltransferase 1 (GGT1))

Binding Specificity: AA 13-225

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GGT1 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Glutathione hydrolase 1 proenzyme protein (13-225AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for GGT1

Target: GGT1 (gamma Glutamyltransferase 1 (GGT1))

Alternative Name: GGT1 (GGT1 Products)

Synonyms: ggt1 antibody, zgc:64172 antibody, CD224 antibody, D22S672 antibody, D22S732 antibody, GGT antibody, GGT 1 antibody, GTG antibody, GGT-1 antibody, Ggtp antibody, dwg antibody, GGLUT antibody, Ggt antibody, GGT2 antibody, cd224 antibody, ggt antibody, gtg antibody, GGT1 antibody, ggt1-a antibody, gamma-glutamyltransferase 1a antibody, gamma-glutamyltransferase 1 antibody, gamma-glutamyltranspeptidase 1 antibody, gamma-glutamyltransferase 1 L homeolog antibody, gamma-glutamyltransferase antibody, gamma-glutamyltranspeptidase Ggt1 antibody, ggt1a antibody, GGT1 antibody, Ggt1 antibody, ggt1 antibody, LOC470168 antibody, ggt1.L antibody, ggt antibody, Bcep18194_A6223 antibody, h16_A1098 antibody, Shewana3_2487 antibody, Bcep1808_2978 antibody

Background:

Background: Cleaves the gamma-glutamyl bond of extracellular glutathione (gamma-Glu-Cys-Gly), glutathione conjugates, and other gamma-glutamyl compounds. The metabolism of glutathione releases free glutamate and the dipeptide, cysteinyl-glycine, which is hydrolyzed to cysteine and glycine by dipeptidases. In the presence of high concentrations of dipeptides and some amino acids, can also catalyze a transpeptidation reaction, transferring the gamma-glutamyl moiety to an acceptor amino acid to form a new gamma-glutamyl compound. Initiates extracellular glutathione (GSH) breakdown, provides cells with a local cysteine supply and contributes to maintain intracellular GSH level. It is part of the cell antioxidant defense mechanism. Isoform 3 seems to be inactive.

Aliases: CD224 antibody, D22S672 antibody, D22S732 antibody, Gamma glutamyl transpeptidase antibody, Gamma glutamyltransferase 1 antibody, Gamma glutamyltranspeptidase 1 antibody, Gamma-glutamyltransferase 1 antibody, Gamma-glutamyltranspeptidase 1 light chain antibody, GGT 1 antibody, GGT antibody, GGT1 antibody, GGT1_HUMAN antibody, Glutamyl transpeptidase antibody, Glutathione hydrolase 1 antibody, GTG antibody, Leukotriene C4 hydrolase antibody, MGC96892 antibody, MGC96904 antibody, MGC96963 antibody, OTTHUMP00000028921 antibody, OTTHUMP00000197959 antibody

UniProt: P19440