GLRX5 antibody (AA 32-157) (Biotin)

Catalog No. ABIN7154053

Product Details anti-GLRX5 Antibody (Biotin)

Target: GLRX5 (Glutaredoxin 5 (GLRX5))

Binding Specificity: AA 32-157

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GLRX5 antibody is conjugated to Biotin

Application: ELISA

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Glutaredoxin-related protein 5, mitochondrial protein (32-157AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for GLRX5

Target: GLRX5 (Glutaredoxin 5 (GLRX5))

Alternative Name: GLRX5 (GLRX5 Products)

Synonyms: grx5 antibody, C14orf87 antibody, FLB4739 antibody, GRX5 antibody, PR01238 antibody, PRO1238 antibody, RGD1308383 antibody, 2310004O13Rik antibody, 2900070E19Rik antibody, AU020725 antibody, id:ibd5119 antibody, wu:fa09g08 antibody, zgc:73343 antibody, glutaredoxin 5 L homeolog antibody, glutaredoxin 5 antibody, glutaredoxin 5 homolog (S. cerevisiae) antibody, glrx5.L antibody, GLRX5 antibody, Glrx5 antibody, glrx5 antibody

Background:

Background: Monothiol glutaredoxin involved in the biogenesis of iron-sulfur clusters (PubMed:20364084). Involved in protein lipoylation, acting in the pathway that provides an iron-sulfur cluster to lipoate synthase (PubMed:24334290). Required for normal iron homeostasis. Required for normal regulation of hemoglobin synthesis by the iron-sulfur protein ACO1 (PubMed:20364084). May protect cells against apoptosis due to reactive oxygen species and oxidative stress (By similarity).

Aliases: C14orf87 antibody, Chromosome 14 open reading frame 87 antibody, FLB4739 antibody, GLRX 5 antibody, Glrx5 antibody, GLRX5_HUMAN antibody, Glutaredoxin 5 homolog antibody, Glutaredoxin related protein 5 antibody, Glutaredoxin-related protein 5 antibody, Glutaredoxin5 antibody, GRX5 antibody, MGC14129 antibody, mitochondrial antibody, Monothiol glutaredoxin-5 antibody, PRO1238 antibody

UniProt: Q86SX6

Pathways: Cell RedoxHomeostasis