Glucagon Receptor antibody (AA 26-136) (HRP)

Catalog No. ABIN7153872

Product Details anti-Glucagon Receptor Antibody (HRP)

Target: Glucagon Receptor (GCGR)

Binding Specificity: AA 26-136

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Glucagon Receptor antibody is conjugated to HRP

Application: ELISA

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Glucagon receptor protein (26-136AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for Glucagon Receptor

Target: Glucagon Receptor (GCGR)

Alternative Name: GCGR (GCGR Products)

Synonyms: GCGR antibody, GGR antibody, GR antibody, glucagon receptor antibody, GCGR antibody, Gcgr antibody

Background:

Background: G-protein coupled receptor for glucagon that plays a central role in the regulation of blood glucose levels and glucose homeostasis. Regulates the rate of hepatic glucose production by promoting glycogen hydrolysis and gluconeogenesis. Plays an important role in mediating the responses to fasting. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Promotes activation of adenylate cyclase. Besides, plays a role in signaling via a phosphatidylinositol-calcium second messenger system.

Aliases: Gcgr antibody, GGR antibody, GL R antibody, GL-R antibody, GLR antibody, GLR_HUMAN antibody, Glucagon receptor antibody, Glucagon receptor precursor antibody, MGC138246 antibody

UniProt: P47871

Pathways: Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process