Phone:
+1 877 302 8632
Fax:
+1 888 205 9894 (Toll-free)
E-Mail:
orders@antibodies-online.com

WDR59 antibody (AA 619-862) (HRP)

WDR59 Reactivity: Human ELISA Host: Rabbit Polyclonal HRP
Catalog No. ABIN7153712
  • Target See all WDR59 products
    WDR59 (WD Repeat Domain 59 (WDR59))
    Binding Specificity
    • 3
    • 1
    • 1
    • 1
    • 1
    AA 619-862
    Reactivity
    • 7
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    Human
    Host
    • 8
    Rabbit
    Clonality
    • 8
    Polyclonal
    Conjugate
    • 6
    • 1
    • 1
    This WDR59 antibody is conjugated to HRP
    Application
    • 6
    • 2
    • 1
    ELISA
    Cross-Reactivity
    Human
    Purification
    >95%, Protein G purified
    Immunogen
    Recombinant Human GATOR complex protein WDR59 protein (619-862AA)
    Isotype
    IgG
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C,-80 °C
    Storage Comment
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target
    WDR59 (WD Repeat Domain 59 (WDR59))
    Alternative Name
    WDR59 (WDR59 Products)
    Synonyms
    5430401O09Rik antibody, Cdw12 antibody, WD repeat domain 59 antibody, WDR59 antibody, Wdr59 antibody
    Background

    Background: As a component of the GATOR subcomplex GATOR2, functions within the amino acid-sensing branch of the TORC1 signaling pathway. Indirectly activates mTORC1 and the TORC1 signaling pathway through the inhibition of the GATOR1 subcomplex (PubMed:23723238). It is negatively regulated by the upstream amino acid sensors SESN2 and CASTOR1 (PubMed:25457612, PubMed:27487210).

    Aliases: WDR59 antibody, KIAA1923 antibody, FP977 antibody, GATOR complex protein WDR59 antibody, WD repeat-containing protein 59 antibody

    UniProt
    Q6PJI9
You are here:
Support