WDR59 antibody (AA 619-862) (HRP)
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- Target See all WDR59 products
- WDR59 (WD Repeat Domain 59 (WDR59))
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Binding Specificity
- AA 619-862
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This WDR59 antibody is conjugated to HRP
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Application
- ELISA
- Cross-Reactivity
- Human
- Purification
- >95%, Protein G purified
- Immunogen
- Recombinant Human GATOR complex protein WDR59 protein (619-862AA)
- Isotype
- IgG
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 - Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Target
- WDR59 (WD Repeat Domain 59 (WDR59))
- Alternative Name
- WDR59 (WDR59 Products)
- Synonyms
- 5430401O09Rik antibody, Cdw12 antibody, WD repeat domain 59 antibody, WDR59 antibody, Wdr59 antibody
- Background
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Background: As a component of the GATOR subcomplex GATOR2, functions within the amino acid-sensing branch of the TORC1 signaling pathway. Indirectly activates mTORC1 and the TORC1 signaling pathway through the inhibition of the GATOR1 subcomplex (PubMed:23723238). It is negatively regulated by the upstream amino acid sensors SESN2 and CASTOR1 (PubMed:25457612, PubMed:27487210).
Aliases: WDR59 antibody, KIAA1923 antibody, FP977 antibody, GATOR complex protein WDR59 antibody, WD repeat-containing protein 59 antibody
- UniProt
- Q6PJI9
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