MIOS antibody (AA 1-237)
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- Target See all MIOS products
- MIOS (WD Repeat-Containing Protein Mio (MIOS))
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Binding Specificity
- AA 1-237
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This MIOS antibody is un-conjugated
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Application
- ELISA, Immunohistochemistry (IHC)
- Cross-Reactivity
- Human
- Purification
- Antigen Affinity Purified
- Immunogen
- Recombinant Human GATOR complex protein MIOS protein (1-237AA)
- Isotype
- IgG
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- Application Notes
- Recommended dilution: IHC:1:20-1:200,
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 - Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Target
- MIOS (WD Repeat-Containing Protein Mio (MIOS))
- Alternative Name
- MIOS (MIOS Products)
- Synonyms
- C81488 antibody, zgc:55958 antibody, meiosis regulator for oocyte development antibody, missing oocyte, meiosis regulator, homolog (Drosophila) antibody, MIOS antibody, Mios antibody, mios antibody
- Background
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Background: As a component of the GATOR subcomplex GATOR2, functions within the amino acid-sensing branch of the TORC1 signaling pathway. Indirectly activates mTORC1 and the TORC1 signaling pathway through the inhibition of the GATOR1 subcomplex (PubMed:23723238). It is negatively regulated by the upstream amino acid sensors SESN2 and CASTOR1 (PubMed:25457612, PubMed:27487210).
Aliases: MIOS antibody, GATOR complex protein MIOS antibody, Missing oocyte meiosis regulator homolog antibody
- UniProt
- Q9NXC5
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