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Gasdermin A antibody (AA 64-172) (HRP)

GSDMA Reactivity: Human ELISA Host: Rabbit Polyclonal HRP
Catalog No. ABIN7153650
  • Target See all Gasdermin A (GSDMA) Antibodies
    Gasdermin A (GSDMA)
    Binding Specificity
    • 15
    • 14
    • 7
    • 3
    • 1
    • 1
    AA 64-172
    Reactivity
    • 34
    • 24
    • 16
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 34
    Rabbit
    Clonality
    • 34
    Polyclonal
    Conjugate
    • 8
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Gasdermin A antibody is conjugated to HRP
    Application
    • 32
    • 17
    • 15
    • 13
    • 13
    • 13
    • 6
    • 3
    • 1
    • 1
    ELISA
    Cross-Reactivity
    Human
    Purification
    >95%, Protein G purified
    Immunogen
    Recombinant Human Gasdermin-A protein (64-172AA)
    Isotype
    IgG
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  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C,-80 °C
    Storage Comment
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target
    Gasdermin A (GSDMA)
    Alternative Name
    GSDMA (GSDMA Products)
    Synonyms
    BB149167 antibody, Gsdm antibody, Gsdm1 antibody, Gsdma1 antibody, H312E antibody, GSDM1 antibody, GSDM antibody, gasdermin A antibody, Gsdma antibody, GSDMA antibody
    Background

    Background: May promote pyroptosis (Probable). Upon cleavage in vitro of genetically engineered GSDMA, the released N-terminal moiety binds to some types of lipids, such as possibly phosphatidylinositol (4,5)-bisphosphate. Homooligomerizes within the membrane and forms pores of 10 -15 nanometers (nm) of inner diameter, triggering cell death. Also binds to bacterial and mitochondrial lipids, including cardiolipin, and exhibits bactericidal activity (PubMed:27281216). The physiological relevance of these observations is unknown (Probable).

    Aliases: GSDMA antibody, GSDM antibody, GSDM1 antibody, FKSG9Gasdermin-A antibody, Gasdermin-1 antibody

    UniProt
    Q96QA5
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