GM2A antibody (AA 32-193)

Catalog No. ABIN7153574

Product Details anti-GM2A Antibody

Target: GM2A (GM2 Ganglioside Activator (GM2A))

Binding Specificity: AA 32-193

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GM2A antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunoprecipitation (IP)

Cross-Reactivity: Human, Mouse, Rat

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Ganglioside GM2 activator protein (32-193AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: WB:1:1000-5000, IHC:1:20-1:200, IP:1:200-1:2000,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for GM2A

Target: GM2A (GM2 Ganglioside Activator (GM2A))

Alternative Name: GM2A (GM2A Products)

Synonyms: GM2A antibody, fb96e04 antibody, fb96e10 antibody, wu:fb96e04 antibody, wu:fb96e10 antibody, zgc:110188 antibody, MGC84154 antibody, GM2-AP antibody, SAP-3 antibody, AA408702 antibody, AW215435 antibody, GM2 ganglioside activator antibody, GM2 ganglioside activator L homeolog antibody, GM2 ganglioside activator protein antibody, Gm2a antibody, GM2A antibody, gm2a antibody, gm2a.L antibody

Background:

Background: The large binding pocket can accommodate several single chain phospholipids and fatty acids, GM2A also exhibits some calcium-independent phospholipase activity (By similarity). Binds gangliosides and stimulates ganglioside GM2 degradation. It stimulates only the breakdown of ganglioside GM2 and glycolipid GA2 by beta-hexosaminidase A. It extracts single GM2 Molecules from membranes and presents them in soluble form to beta-hexosaminidase A for cleavage of N-acetyl-D-galactosamine and conversion to GM3.

Aliases: Cerebroside sulfate activator protein antibody, ganglioside GM2 activator antibody, Ganglioside GM2 activator isoform short antibody, Ganglioside GM2 activator precursor antibody, GM2 activator antibody, GM2 AP antibody, GM2 ganglioside activator antibody, GM2 ganglioside activator protein antibody, GM2-AP antibody, GM2A antibody, GM2AP antibody, OTTHUMP00000160619 antibody, SAP 3 antibody, SAP-3 antibody, SAP3 antibody, SAP3_HUMAN antibody, Shingolipid activator protein 3 antibody, Sphingolipid activator protein 3 antibody

UniProt: P17900