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GPR161 antibody (AA 1-28)

GPR161 Reactivity: Human WB, ELISA, IF Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7153327
  • Target See all GPR161 Antibodies
    GPR161 (G Protein-Coupled Receptor 161 (GPR161))
    Binding Specificity
    • 15
    • 5
    • 4
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-28
    Reactivity
    • 46
    • 10
    • 7
    • 7
    • 6
    • 6
    • 6
    • 5
    • 5
    • 5
    • 1
    • 1
    Human
    Host
    • 44
    • 2
    Rabbit
    Clonality
    • 44
    • 2
    Polyclonal
    Conjugate
    • 20
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This GPR161 antibody is un-conjugated
    Application
    • 33
    • 15
    • 13
    • 13
    • 12
    • 9
    • 3
    • 2
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (IF)
    Cross-Reactivity
    Human
    Purification
    >95%, Protein G purified
    Immunogen
    Recombinant Human G-protein coupled receptor 161 protein (1-28AA)
    Isotype
    IgG
    Top Product
    Discover our top product GPR161 Primary Antibody
  • Application Notes
    Recommended dilution: WB:1:1000-1:5000, IF:1:50-1:200,
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C,-80 °C
    Storage Comment
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target
    GPR161 (G Protein-Coupled Receptor 161 (GPR161))
    Alternative Name
    GPR161 (GPR161 Products)
    Synonyms
    RE2 antibody, Gm208 antibody, Gm208Gpr antibody, vl antibody, RGD1563245 antibody, si:bz20i5.4 antibody, si:rp71-20i5.4 antibody, G protein-coupled receptor 161 antibody, GPR161 antibody, Gpr161 antibody, gpr161 antibody
    Background

    Background: Key negative regulator of Shh signaling, which promotes the processing of GLI3 into GLI3R during neural tube development. Recruited by TULP3 and the IFT-A complex to primary cilia and acts as a regulator of the PKA-dependent basal repression machinery in Shh signaling by increasing cAMP levels, leading to promote the PKA-dependent processing of GLI3 into GLI3R and repress the Shh signaling. In presence of SHH, it is removed from primary cilia and is internalized into recycling endosomes, preventing its activity and allowing activation of the Shh signaling. Its ligand is unknown (By similarity).

    Aliases: GPR161 antibody, G-protein coupled receptor 161 antibody, G-protein coupled receptor RE2 antibody

    UniProt
    Q8N6U8
    Pathways
    cAMP Metabolic Process
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