Phone:
+1 877 302 8632
Fax:
+1 888 205 9894 (Toll-free)
E-Mail:
orders@antibodies-online.com

GRK6 antibody (AA 1-170)

GRK6 Reactivity: Human ELISA, IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7153301
  • Target See all GRK6 Antibodies
    GRK6 (G Protein-Coupled Receptor Kinase 6 (GRK6))
    Binding Specificity
    • 8
    • 5
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-170
    Reactivity
    • 38
    • 23
    • 17
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Human
    Host
    • 33
    • 5
    Rabbit
    Clonality
    • 35
    • 3
    Polyclonal
    Conjugate
    • 26
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This GRK6 antibody is un-conjugated
    Application
    • 31
    • 16
    • 13
    • 6
    • 4
    • 3
    • 2
    ELISA, Immunohistochemistry (IHC)
    Cross-Reactivity
    Human
    Purification
    Antigen Affinity Purified
    Immunogen
    Recombinant Human G protein-coupled receptor kinase 6 protein (1-170AA)
    Isotype
    IgG
    Top Product
    Discover our top product GRK6 Primary Antibody
  • Application Notes
    Recommended dilution: IHC:1:20-1:200,
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C,-80 °C
    Storage Comment
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target
    GRK6 (G Protein-Coupled Receptor Kinase 6 (GRK6))
    Alternative Name
    GRK6 (GRK6 Products)
    Synonyms
    MGC83187 antibody, GRK6 antibody, GPRK6 antibody, Gprk6 antibody, G protein-coupled receptor kinase 6 antibody, G protein-coupled receptor kinase 6 S homeolog antibody, GRK6 antibody, grk6.S antibody, grk6 antibody, Grk6 antibody
    Background

    Background: Specifically phosphorylates the activated forms of G protein-coupled receptors. Such receptor phosphorylation initiates beta-arrestin-mediated receptor desensitization, internalization, and signaling events leading to their desensitization. Seems to be involved in the desensitization of D2-like dopamine receptors in striatum and chemokine receptor CXCR4 which is critical for CXCL12-induced cell chemotaxis (By similarity). Phosphorylates rhodopsin (RHO) (in vitro) and a non G-protein-coupled receptor: LRP6 during Wnt signaling (in vitro).

    Aliases: FLJ32135 antibody, G protein coupled receptor kinase 6 antibody, G protein coupled receptor kinase GRK6 antibody, G protein-coupled receptor kinase 6 antibody, G protein-coupled receptor kinase GRK6 antibody, Gprk6 antibody, Grk6 antibody, GRK6_HUMAN antibody

    UniProt
    P43250
    Pathways
    Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling, CXCR4-mediated Signaling Events, Negative Regulation of Transporter Activity
You are here:
Support