GRK4 antibody (AA 1-245)

Catalog No. ABIN7153293

Product Details anti-GRK4 Antibody

Target: GRK4 (G Protein-Coupled Receptor Kinase 4 (GRK4))

Binding Specificity: AA 1-245

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GRK4 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human G protein-coupled receptor kinase 4 protein (1-245AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200, IF:1:50-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for GRK4

Target: GRK4 (G Protein-Coupled Receptor Kinase 4 (GRK4))

Alternative Name: GRK4 (GRK4 Products)

Synonyms: GPRK2L antibody, GPRK4 antibody, GRK4a antibody, IT11 antibody, A830025H08Rik antibody, GRK antibody, Gprk2l antibody, Gprk4 antibody, AMPK antibody, AMPKalpha antibody, CG3051 antibody, DmAMPK alpha antibody, Dmel\\CG3051 antibody, EG:132E8.2 antibody, FBgn0023169 antibody, Gprk-4 antibody, ampk antibody, ampkalpha antibody, dAMPKa antibody, dAMPKalpha antibody, snf1a antibody, gprk4 antibody, gprk4-a antibody, grk4 antibody, GRK4 antibody, gprk4-b antibody, zgc:153020 antibody, gprk2l antibody, grk4a antibody, it11 antibody, G protein-coupled receptor kinase 4 antibody, AMP-activated protein kinase alpha subunit antibody, G protein-coupled receptor kinase 4 L homeolog antibody, G protein-coupled receptor kinase 4 S homeolog antibody, GRK4 antibody, Grk4 antibody, AMPKalpha antibody, grk4.L antibody, grk4.S antibody, grk4 antibody, LOC100540688 antibody

Background:

Background: Specifically phosphorylates the activated forms of G protein-coupled receptors. GRK4-alpha can phosphorylate rhodopsin and its activity is inhibited by calmodulin, the other three isoforms do not phosphorylate rhodopsin and do not interact with calmodulin. GRK4-alpha and GRK4-gamma phosphorylate DRD3. Phosphorylates ADRB2.

Aliases: G protein coupled receptor kinase 4 antibody, G protein-coupled receptor kinase 2 (Drosophila)-like antibody, G protein-coupled receptor kinase 4 antibody, G protein-coupled receptor kinase GRK4 antibody, G proteinm coupled receptor kinase GRK4 antibody, GPRK2L antibody, GPRK4 antibody, GRK4 antibody, GRK4_HUMAN antibody, GRK4a antibody, ITI1 antibody

UniProt: P32298

Pathways: Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling